Department of Gastroenterology and Hepatology, Health Research Institute, University Hospital of Santiago de Compostela, Spain.
Centre for Pancreatic Diseases, Department of Gastroenterology, Aalborg University Hospital, Denmark.
Pancreatology. 2018 Dec;18(8):847-854. doi: 10.1016/j.pan.2018.09.016. Epub 2018 Oct 6.
In collaboration with United European Gastroenterology, the working group on 'Harmonizing diagnosis and treatment of chronic pancreatitis across Europe' (HaPanEU) developed European guidelines for the management of chronic pancreatitis using an evidence-based approach.
Recommendations of multidisciplinary review groups based on systematic literature reviews to answer predefined clinical questions are summarised. Recommendations are graded using the Grading of Recommendations Assessment, Development and Evaluation system.
Recommendations covered topics related to the clinical management of chronic pancreatitis: aetiology, diagnosis of chronic pancreatitis with imaging, diagnosis of pancreatic exocrine insufficiency, surgical therapy, medical therapy, endoscopic therapy, treatment of pancreatic pseudocysts, pancreatic pain, nutrition and malnutrition, diabetes mellitus and the natural course of the disease and quality of life.
The HaPanEU/United European Gastroenterology guidelines provide evidence-based recommendations concerning key aspects of the medical and surgical management of chronic pancreatitis based on current available evidence. These recommendations should serve as a reference standard for existing management of the disease and as a guide for future clinical research. This article summarises the HaPanEU recommendations and statements.
与欧洲联合胃肠病学学会合作，“在欧洲协调慢性胰腺炎的诊断和治疗”工作组（HaPanEU）采用循证方法制定了慢性胰腺炎管理的欧洲指南。
根据系统文献回顾，多学科审查小组的建议总结了预先确定的临床问题。建议使用推荐评估、制定和评估系统进行分级。
建议涵盖了与慢性胰腺炎临床管理相关的主题：病因、影像学诊断慢性胰腺炎、胰腺外分泌功能不全的诊断、手术治疗、药物治疗、内镜治疗、胰腺假性囊肿治疗、胰腺疼痛、营养和营养不良、糖尿病以及疾病的自然病程和生活质量。
HaPanEU/欧洲联合胃肠病学学会指南提供了基于现有证据的关于慢性胰腺炎的医学和外科治疗的关键方面的循证建议。这些建议应作为现有疾病管理的参考标准，并作为未来临床研究的指南。本文总结了 HaPanEU 的建议和声明。
