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Comparison of modified versus conventional injection techniques of low-molecular-weight heparin in elderly.老年患者中低分子量肝素改良注射技术与传统注射技术的比较。
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Slow versus fast subcutaneous heparin injections for prevention of bruising and site pain intensity.皮下注射肝素时慢速与快速注射对预防瘀伤及注射部位疼痛强度的影响
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Expanding eligibility for outpatient treatment of deep venous thrombosis and pulmonary embolism with low-molecular-weight heparin: a comparison of patient self-injection with homecare injection.扩大低分子量肝素用于门诊治疗深静脉血栓形成和肺栓塞的适用范围：患者自我注射与家庭护理注射的比较
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The effect of a seven-step rehabilitation training program on cardiac function and quality of life after percutaneous coronary intervention for acute myocardial infarction.七步康复训练计划对急性心肌梗死经皮冠状动脉介入治疗后心脏功能和生活质量的影响。
Pak J Med Sci. 2022 Jan-Feb;38(1):123-127. doi: 10.12669/pjms.38.1.4945.

本文引用的文献

1
Slow versus fast subcutaneous heparin injections for prevention of bruising and site-pain intensity.皮下注射肝素时慢速与快速注射预防瘀伤及注射部位疼痛强度的比较
Cochrane Database Syst Rev. 2014 Jul 18(7):CD008077. doi: 10.1002/14651858.CD008077.pub3.
2
The effect of injection duration and injection site on pain and bruising of subcutaneous injection of heparin.注射持续时间和注射部位对皮下注射肝素时疼痛和瘀伤的影响。
J Clin Nurs. 2014 Apr;23(7-8):1105-13. doi: 10.1111/jocn.12291. Epub 2013 Jul 12.
3
Unfractionated heparin versus low molecular weight heparin for avoiding heparin-induced thrombocytopenia in postoperative patients.普通肝素与低分子量肝素用于预防术后患者肝素诱导的血小板减少症的比较
Cochrane Database Syst Rev. 2012 Sep 12(9):CD007557. doi: 10.1002/14651858.CD007557.pub2.
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Drug use problems with self-injected low-molecular-weight heparins in primary care.基层医疗中自我注射低分子肝素的药物使用问题。
Eur J Clin Pharmacol. 2011 Feb;67(2):109-20. doi: 10.1007/s00228-010-0956-5. Epub 2010 Nov 24.
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Current dosing of low-molecular-weight heparins does not reflect licensed product labels: an international survey.目前低分子肝素的给药剂量并不反映许可产品标签：一项国际调查。
Br J Clin Pharmacol. 2010 May;69(5):520-8. doi: 10.1111/j.1365-2125.2010.03626.x.
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A study on the effect of the duration of subcutaneous heparin injection on bruising and pain.皮下注射肝素的持续时间对瘀伤和疼痛影响的研究。
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老年患者中低分子量肝素改良注射技术与传统注射技术的比较。

Comparison of modified versus conventional injection techniques of low-molecular-weight heparin in elderly.

作者信息

Geng Wenzhen, Zhang Ying, Shi Juan

机构信息

Wenzhen Geng, Internal Medicine Cardiovascular Department, Binzhou People's Hospital, Shandong, 256610, China.

Ying Zhang, Pediatric Intensive Care Unit, Binzhou People's Hospital, Shandong, 256610, China.

出版信息

Pak J Med Sci. 2018 Sep-Oct;34(5):1142-1145. doi: 10.12669/pjms.345.15466.

DOI:10.12669/pjms.345.15466
PMID:30344565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6191786/
Abstract

OBJECTIVE

To analyze the clinical values of modified injection of low-molecular-weight heparin in reducing subcutaneous bleeding and pain.

METHODS

Two hundred and sixty patients with cerebral infarction, acute myocardial infarction or pulmonary embolism who underwent subcutaneous injection of low-molecular weight heparin in the hospital between December 2015 and December 2016 were selected. They were randomly divided into a control group and a research group, 130 each. Patients in the control group were given conventional injection, while patients in the research group were given modified injection. The occurrence of subcutaneous bleeding and pain was observed and compared between the two groups.

RESULTS

The incidence of subcutaneous hemorrhage in the research group was 46.9%, significantly lower than 83.1% in the control group, and the difference had statistical significance (P<0.05). Twenty-six patients in the control group had severe pain, which was much more than 5 patients in the research group, and the difference was statistically significant (P<0.05). The number of cases of severe hemorrhage in the control group was significantly larger than that of the research group (31 vs. 3), and the difference was also statistically significant.

CONCLUSION

Modified low-molecular weight heparin injection can effectively reduce the incidence of bleeding and pain, which is beneficial to the compliance and quality of life of elder patients.

摘要

目的

分析改良低分子肝素注射在减少皮下出血和疼痛方面的临床价值。

方法

选取2015年12月至2016年12月在我院接受皮下注射低分子肝素的260例脑梗死、急性心肌梗死或肺栓塞患者。将他们随机分为对照组和研究组，每组130例。对照组患者采用常规注射，研究组患者采用改良注射。观察并比较两组患者皮下出血和疼痛的发生情况。

结果

研究组皮下出血发生率为46.9%，显著低于对照组的83.1%，差异有统计学意义（P<0.05）。对照组有26例患者出现重度疼痛，明显多于研究组的5例，差异有统计学意义（P<0.05）。对照组严重出血病例数显著多于研究组（31例对3例），差异也有统计学意义。

结论

改良低分子肝素注射可有效降低出血和疼痛发生率，有利于老年患者的依从性和生活质量。