Levin O S, Chimagomedova A Sh, Polyakova T A, Arablinsky A V
Russian Medical Academy of Continuous Professional Education, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(6. Vyp. 2):13-26. doi: 10.17116/jnevro201811806213.
The term 'dyscirculatory encephalopathy' (DEP) was proposed in 1958 by Garun Maksudov and Vladimir Kogan for the definition of gradually progressive diffuse brain changes with slowly worsening of cerebral circulation ('dyscirculation') in vascular disorders. The article presents current data on the etiology and pathogenesis of DEP, with the emphasis on its syndromal status, clinical/pathogenetic types of DEP, neuropsychological and neuroimaging signs, which provide a causal relationship to avoid hyperdiagnosis of DEP. In addition, possible methods of treatment and prevention of DEP are considered.
“循环障碍性脑病”（DEP）这一术语于1958年由加伦·马克苏多夫和弗拉基米尔·科根提出，用于定义血管疾病中随着脑循环逐渐恶化（“循环障碍”）而出现的渐进性弥漫性脑改变。本文介绍了关于DEP病因和发病机制的当前数据，重点阐述了其综合征状态、DEP的临床/病理生理类型、神经心理学和神经影像学特征，这些特征提供了因果关系，以避免对DEP的过度诊断。此外，还考虑了DEP可能的治疗和预防方法。
