Department of Chemistry , University of Toronto ; 80 St. George Street , Toronto , ON M5S 3H6 , Canada.
Environ Sci Technol. 2018 Nov 20;52(22):13195-13201. doi: 10.1021/acs.est.8b03880. Epub 2018 Oct 31.
Third-hand smoke (THS) is an emerging route of exposure to tobacco smoke in the indoor environment. Few studies have investigated the chemical behavior of THS, although initial findings suggest that semivolatile components of THS can partition to indoor aerosol. By exposing single-component particles to THS in an environmental chamber, this study demonstrates a pronounced dependence of THS uptake on aerosol composition. First, it was found that primarily reduced nitrogen compounds (that produced C H N ion signal) in THS partitioned strongly to acidic ammoniated sulfate particles, whereas overall THS uptake to more pH-neutral sodium sulfate particles was minimal. Second, THS uptake to pure hydrocarbon particles (squalane) was even greater than to ammoniated sulfate particles with the uptake arising from mainly C H compounds. The greater uptake of THS to squalane was mostly driven by the dominant fraction of C H compounds in the side stream cigarette smoke aerosol, the composition of which is likely to be broadly similar to THS in these experiments. Third, oxygenated organic particles (sucrose) and solid ammonium sulfate particles showed minimal uptake. These results indicate that particulate THS inhalation exposure will be strongly dependent on the chemical nature of the particles present in the indoor environment.
三手烟（THS）是室内环境中接触烟草烟雾的一种新途径。尽管初步研究结果表明，THS 的半挥发性成分可以分配到室内气溶胶中，但很少有研究调查 THS 的化学行为。本研究通过在环境室中使单一组分的颗粒暴露于 THS，证明了 THS 摄取对气溶胶组成的明显依赖性。首先，发现 THS 中的主要还原氮化合物（产生 C H N 离子信号）强烈分配到酸性氨化硫酸盐颗粒上，而对更中性 pH 的硫酸钠颗粒的总体 THS 摄取则最小。其次，THS 对纯碳氢化合物颗粒（角鲨烷）的摄取甚至大于对氨化硫酸盐颗粒的摄取，这主要归因于侧流香烟烟雾气溶胶中的主要 C H 化合物。THS 对角鲨烷的更大摄取主要由侧流香烟烟雾气溶胶中的主要 C H 化合物组成，其组成在这些实验中可能与 THS 大致相似。第三，含氧有机颗粒（蔗糖）和固体硫酸铵颗粒的摄取最小。这些结果表明，颗粒态 THS 吸入暴露将强烈取决于室内环境中存在的颗粒的化学性质。
