Department of Surgery, University Hospital Limerick, Limerick, Ireland; Graduate Entry Medical School, University of Limerick, Limerick, Ireland.
Graduate Entry Medical School, University of Limerick, Limerick, Ireland.
Semin Cell Dev Biol. 2019 Aug;92:55-62. doi: 10.1016/j.semcdb.2018.10.005. Epub 2018 Oct 25.
Mesothelial, neurovascular, lymphatic, adipose and mesenchymal tissues make up the mesentery. These tissues are pathobiologically important for numerous reasons. Collectively, they form a continuous, discrete and substantive organ. Additionally, they maintain abdominal digestive organs in position and in continuity with other systems. Furthermore, as they occupy a central position, they mediate transmission of signals between the abdominal digestive system and the remainder of the body. Despite this physiologic centrality, mesenteric tissue development has received little investigatory focus. However, recent advances in our understanding of anatomy demonstrate continuity between all mesenteric tissues, thereby linking previously unrelated studies. In this review, we examine the development of mesenteric tissue in normality and in the setting of congenital abnormalities.
间皮、神经血管、淋巴管、脂肪和间充质组织构成了肠系膜。这些组织在许多方面都具有重要的病理生物学意义。它们共同形成了一个连续的、离散的实质性器官。此外，它们将腹部消化器官固定在适当的位置，并与其他系统保持连续性。此外，由于它们处于中心位置，它们在腹部消化系统和身体其他部位之间传递信号。尽管具有这种生理中心性，但肠系膜组织的发育很少受到研究关注。然而，我们对解剖学理解的最新进展表明所有肠系膜组织之间具有连续性，从而将以前不相关的研究联系起来。在这篇综述中，我们检查了正常和先天性异常情况下肠系膜组织的发育。
