成人桥小脑角原发性胶质母细胞瘤酷似听神经瘤
Primary Glioblastoma of Cerebellopontine Angle in Adult Mimicking Acoustic Neuroma.
作者信息
Yang Dian-Xu, Jing Yao, Xu Zhi-Ming, Yuan Fang, Liu Ying-Liang, Wang Gui-Song, Tian Heng-Li
机构信息
Department of Neurosurgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
出版信息
World Neurosurg. 2019 Feb;122:48-52. doi: 10.1016/j.wneu.2018.10.073. Epub 2018 Oct 19.
BACKGROUND
Gliomas are usually located in the supratentorial region and are extremely rare at the cerebellopontine angle (CPA). Consequently, gliomas in the CPA are easy to misdiagnose preoperatively.
CASE DESCRIPTION
This paper presents a 55-year-old man with an extraaxial CPA glioblastoma arising from the proximal portion of cranial nerve (CN) VIII. Preoperative imaging findings suggested an acoustic neuroma. The tumor was removed subtotally, and it was completely separated from the brainstem and cerebellum. The histopathologic examination showed a glioblastoma.
CONCLUSIONS
To our knowledge, this case is the second report of a true primary extraaxial CPA glioblastoma. Therefore glioma should be considered in the differential diagnosis of CPA masses with atypical imaging features, although they are extremely rare.
背景
胶质瘤通常位于幕上区域，在桥小脑角（CPA）极为罕见。因此，CPA区的胶质瘤术前很容易误诊。
病例描述
本文介绍了一名55岁男性，患有起源于第八对颅神经（CN）近端的轴外CPA胶质母细胞瘤。术前影像学检查结果提示为听神经瘤。肿瘤次全切除，与脑干和小脑完全分离。组织病理学检查显示为胶质母细胞瘤。
结论
据我们所知，该病例是真正原发性轴外CPA胶质母细胞瘤的第二例报道。因此，尽管CPA区肿块合并非典型影像学特征的胶质瘤极为罕见，但在鉴别诊断时仍应考虑到。
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