Pulmonary & Critical Care, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Cedars-Sinai Medical Center, Los Angeles, CA, USA.
J Intensive Care Med. 2020 Oct;35(10):1032-1038. doi: 10.1177/0885066618807859. Epub 2018 Oct 22.
Computed tomography angiography is limited in the intensive care unit (ICU) due to renal insufficiency, hemodynamic instability, and difficulty transporting unstable patients. A portable ventilation/perfusion (V/Q) scan can be used. However, it is commonly believed that an abnormal chest radiograph can result in a nondiagnostic scan. In this retrospective study, we demonstrate that portable V/Q scans can be helpful in ruling in or out clinically significant pulmonary embolism (PE) despite an abnormal chest x-ray in the ICU.
Two physicians conducted chart reviews and original V/Q reports. A staff radiologist, with 40 years of experience, rated chest x-ray abnormalities using predetermined criteria.
The study was conducted in the ICU.
The first 100 consecutive patients with suspected PE who underwent a portable V/Q scan.
Those with a portable V/Q scan.
A normal baseline chest radiograph was found in only 6% of patients. Fifty-three percent had moderate, 24% had severe, and 10% had very-severe radiographic abnormalities. Despite the abnormal x-rays, 88% of the V/Q scans were low probability for a PE despite an average abnormal radiograph rating of moderate. A high-probability V/Q for PE was diagnosed in 3% of the population despite chest x-ray ratings of moderate to severe. Six patients had their empiric anticoagulation discontinued after obtaining the results of the V/Q scan, and no anticoagulation was started for PE after a low-probability V/Q scan.
Despite the large percentage of moderate-to-severe x-ray abnormalities, PE can still be diagnosed (high-probability scan) in the ICU with a portable V/Q scan. Although low-probability scans do not rule out acute PE, it appeared less likely that any patient with a low-probability V/Q scan had severe hypoxemia or hemodynamic instability due to a significant PE, which was useful to clinicians and allowed them to either stop or not start anticoagulation.
由于肾功能不全、血流动力学不稳定以及难以转运不稳定患者,计算机断层血管造影术(CTA)在重症监护病房(ICU)受到限制。可以使用便携式通气/灌注(V/Q)扫描。但是,通常认为异常的胸部 X 射线会导致扫描结果不可诊断。在这项回顾性研究中,我们证明,尽管 ICU 中的胸部 X 射线异常,便携式 V/Q 扫描仍有助于排除或确定临床上显著的肺栓塞(PE)。
两位医生进行了图表审查和原始 V/Q 报告。一位拥有 40 年经验的工作人员放射科医师使用预定标准对胸部 X 射线异常进行评分。
该研究在 ICU 进行。
首位连续 100 例疑似 PE 患者进行了便携式 V/Q 扫描。
进行便携式 V/Q 扫描的患者。
只有 6%的患者的基线胸部 X 射线正常。53%的患者存在中度异常,24%的患者存在重度异常,10%的患者存在非常严重的放射学异常。尽管 X 射线异常,88%的 V/Q 扫描结果为 PE 低概率,尽管平均 X 射线异常评分中度。尽管胸部 X 射线评分为中度至重度,但仍有 3%的患者被诊断为 V/Q 扫描为 PE 高概率。6 例患者在获得 V/Q 扫描结果后停止了经验性抗凝治疗,而低概率 V/Q 扫描后未开始针对 PE 的抗凝治疗。
尽管存在大量中度至重度 X 射线异常,但仍可在 ICU 中使用便携式 V/Q 扫描诊断 PE(高概率扫描)。尽管低概率扫描不能排除急性 PE,但似乎不太可能有任何低概率 V/Q 扫描的患者因严重低氧血症或血流动力学不稳定而发生显著的 PE,这对临床医生有用,使他们能够停止或不开始抗凝治疗。