Baurmann H, Chioralia G, Kremer F
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1977 Sep 30;204(1):45-55. doi: 10.1007/BF02387416.
The corneal neovascularization produced by NaOH burns was examined in two groups of pigmented rabbits following laser treatment. The treatment was carried out with energy level 500 mW, spot diameter 200 micron, and exposure time 1 s throughout. In the first group, a single newly formed vessel was coagulated in each case. Subsequent fluorescein angiography invariably showed an incomplete occlusion of the vessel. In the second group, we coagulated a section of the neovascularization network at its origin in the corneal limbus. After 48 h, fluorescein perfusion was once again observed, but the vessels were predominantly finer than before. Fluorescence microscopy revealed a rich neovascularization of the more superficial layers of the corneal stroma. To be successful, laser treatment must involve both supplying and draining vessels.
在两组有色兔中,对氢氧化钠烧伤所致的角膜新生血管进行了激光治疗后的检查。整个治疗过程的能量水平为500毫瓦,光斑直径为200微米,曝光时间为1秒。在第一组中,每种情况下均对一条新形成的血管进行凝固。随后的荧光血管造影始终显示血管闭塞不完全。在第二组中,我们在角膜缘新生血管网络的起始处凝固了一段。48小时后,再次观察到荧光素灌注,但血管主要比以前更细。荧光显微镜检查显示角膜基质较浅层有丰富的新生血管。要取得成功,激光治疗必须涉及供血和引流血管。