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Bortezomib-based chemotherapy in mantle cell lymphoma.

作者信息

Rule Simon

机构信息

University of Plymouth Medical School and Department of Haematology, Plymouth University NHS Trust, Plymouth, PL6 8DH, UK.

出版信息

Lancet Oncol. 2018 Nov;19(11):1419-1421. doi: 10.1016/S1470-2045(18)30743-5. Epub 2018 Oct 19.

DOI:10.1016/S1470-2045(18)30743-5
PMID:30348536
Abstract
摘要

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Efficacy and safety of frontline rituximab, cyclophosphamide, doxorubicin and prednisone plus bortezomib (VR-CAP) or vincristine (R-CHOP) in a subset of newly diagnosed mantle cell lymphoma patients medically eligible for transplantation in the randomized, phase 3 LYM-3002 study.在随机3期LYM-3002研究中,一线利妥昔单抗、环磷酰胺、阿霉素和泼尼松联合硼替佐米(VR-CAP)或长春新碱(R-CHOP)对一部分新诊断的符合移植医学标准的套细胞淋巴瘤患者的疗效和安全性。
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Bortezomib plus CHOP-rituximab for previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma.硼替佐米联合 CHOP-利妥昔单抗方案治疗初治弥漫性大 B 细胞淋巴瘤和套细胞淋巴瘤。
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Phase II trial of R-CHOP plus bortezomib induction therapy followed by bortezomib maintenance for newly diagnosed mantle cell lymphoma: SWOG S0601.R-CHOP方案联合硼替佐米诱导治疗继以硼替佐米维持治疗初诊套细胞淋巴瘤的II期试验:SWOG S0601
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Granulocyte-macrophage colony stimulating factor-induced immune priming of cyclophosphamide, doxorubicin, vincristine, and prednisone with rituximab chemoimmunotherapy in previously untreated patients with diffuse large B-cell lymphoma and mantle cell lymphoma.粒细胞-巨噬细胞集落刺激因子诱导的免疫启动联合环磷酰胺、多柔比星、长春新碱和泼尼松与利妥昔单抗化疗免疫治疗在未经治疗的弥漫性大 B 细胞淋巴瘤和套细胞淋巴瘤患者中的应用。
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Immunochemotherapy with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone significantly improves response and time to treatment failure, but not long-term outcome in patients with previously untreated mantle cell lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Study Group (GLSG).利妥昔单抗联合环磷酰胺、阿霉素、长春新碱及泼尼松进行免疫化疗可显著提高反应率并延长至治疗失败时间,但对既往未治疗的套细胞淋巴瘤患者的长期预后无改善:德国低度淋巴瘤研究组(GLSG)一项前瞻性随机试验的结果
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