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主动脉食管瘘:胸段血管腔内主动脉支架移植物置入术的致命并发症

Aortoesophageal Fistula: A Fatal Complication of Thoracic Endovascular Aortic Stent-Graft Placement.

作者信息

Rawala Muhammad Shabbir, Badami Varun, Rizvi Syed Bilal, Nanjundappa Aravinda

机构信息

Department of Internal Medicine, West Virginia University (WVU) - Charleston Division, Charleston, WV, USA.

Department of Internal Medicine, West Virginia University (WVU) - Morgantown Division, Morgantown, WV, USA.

出版信息

Am J Case Rep. 2018 Oct 23;19:1258-1261. doi: 10.12659/AJCR.911441.

Abstract

BACKGROUND Hemetemesis is rarely caused by an aorta-esophageal fistula with thoracic aorta aneurysm in patients. This uncommon etiology, AEF/TAA, can potentially rupture and cause death if left untreated. Thoracic endovascular aorta repair places a stent-graft to seal the aneurysm and cover the fistulous track. Open surgical repair is associated with high risk of morbidity and mortality; therefore, TEVAR is a much safer alternative to it. However, recurrent or persistent infection remains a major concern with TEVAR for AEF. CASE REPORT We present a rare case of an 80-year-old woman who presented with complaints of hemetemesis and epigastric pain. The patient underwent a computerized tomography scan, highlighting a TAA and AEF. A stent was placed in the descending thoracic aorta via endovascular approach and a subsequent EGD was negative for any residual bleeding. Methicillin-resistant Staphylococcus aureus was isolated from the patient's sputum cultures and she was treated with a prolonged course of antibiotics. She presented to the hospital a few weeks later with new-onset hematemesis. Workup identified an AEF. The patient was high risk for open surgical repair due to her comorbid conditions; therefore, an esophageal stent was placed. She was diagnosed with AEF secondary to an infected endovascular thoracic aorta stent. CONCLUSIONS Patients who are high risk for open surgical repair from immediate rupture of TAA with AEF can benefit from use of the TEVAR approach. The stent itself is a foreign body; therefore, the risk of infection persists. AEF is a rare but potentially fatal complication of the infected thoracic aortic stent itself.

摘要

背景 呕血在患者中很少由胸主动脉瘤导致的主动脉 - 食管瘘引起。这种不常见的病因,即主动脉 - 食管瘘/胸主动脉瘤(AEF/TAA),如果不治疗可能会破裂并导致死亡。胸主动脉腔内修复术是放置覆膜支架来封闭动脉瘤并覆盖瘘道。开放手术修复的发病率和死亡率风险很高;因此,胸主动脉腔内修复术(TEVAR)是一种更安全的替代方法。然而,TEVAR治疗AEF时,感染复发或持续仍然是一个主要问题。病例报告 我们报告一例罕见的80岁女性病例,她因呕血和上腹部疼痛就诊。患者接受了计算机断层扫描,显示有胸主动脉瘤和主动脉 - 食管瘘。通过血管腔内方法在胸降主动脉放置了一个支架,随后的上消化道内镜检查未发现任何残留出血。从患者的痰培养物中分离出耐甲氧西林金黄色葡萄球菌,她接受了长时间的抗生素治疗。几周后她再次入院,出现新的呕血症状。检查发现有主动脉 - 食管瘘。由于她的合并症,患者进行开放手术修复的风险很高;因此,放置了食管支架。她被诊断为因感染性胸主动脉腔内支架继发的主动脉 - 食管瘘。结论 因胸主动脉瘤合并主动脉 - 食管瘘立即破裂而进行开放手术修复风险高的患者可从TEVAR方法中获益。支架本身是异物;因此,感染风险仍然存在。主动脉 - 食管瘘是感染性胸主动脉支架本身罕见但可能致命的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4a0/6206620/4bccef546832/amjcaserep-19-1258-g001.jpg

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