An HTS FP assay able to selectively identify STAT3-DBD inhibitors.
作者信息
Meneghetti Fiorella, Barlocco Daniela
机构信息
Fiorella Meneghetti: Department of Pharmaceutical Sciences, University of Milan, Milano, Italy.
出版信息
Oncotarget. 2018 Oct 2;9(77):34451-34452. doi: 10.18632/oncotarget.26155.
Abstract
摘要
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本文引用的文献
1
A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3).一种用于发现靶向信号转导和转录激活因子3（STAT3）DNA结合结构域抑制剂的高通量荧光偏振分析方法。
Oncotarget. 2018 Aug 24;9(66):32690-32701. doi: 10.18632/oncotarget.26013.
2
Two decades of research in discovery of anticancer drugs targeting STAT3, how close are we?针对 STAT3 的抗癌药物的发现：二十年的研究，我们已经走了多远？
Pharmacol Ther. 2018 Nov;191:74-91. doi: 10.1016/j.pharmthera.2018.06.006. Epub 2018 Jun 20.
3
An in vivo active 1,2,5-oxadiazole Pt(II) complex: A promising anticancer agent endowed with STAT3 inhibitory properties.一种体内活性的1,2,5-恶二唑铂（II）配合物：一种具有STAT3抑制特性的有前景的抗癌剂。
Eur J Med Chem. 2017 May 5;131:196-206. doi: 10.1016/j.ejmech.2017.03.017. Epub 2017 Mar 15.
4
A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3.一种用于转录信号转导子与激活子3的高通量荧光偏振检测法。
Anal Biochem. 2004 Jul 1;330(1):114-8. doi: 10.1016/j.ab.2004.03.024.
5
Stat3 as an oncogene.作为癌基因的信号转导与转录激活因子3（Stat3）
Cell. 1999 Aug 6;98(3):295-303. doi: 10.1016/s0092-8674(00)81959-5.
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