• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Major lower limb amputation audit - introduction and implementation of a multimodal perioperative pain management guideline.下肢大截肢审计——多模式围手术期疼痛管理指南的介绍与实施
Br J Pain. 2018 Nov;12(4):230-237. doi: 10.1177/2049463718769339. Epub 2018 Apr 18.
2
A pre-emptive multimodal pathway featuring peripheral nerve block improves perioperative outcomes after major orthopedic surgery.以周围神经阻滞为特色的多模式预先镇痛途径可改善骨科大手术后的围手术期结局。
Reg Anesth Pain Med. 2008 Nov-Dec;33(6):510-7.
3
Preoperative multimodal analgesia decreases 24-hour postoperative narcotic consumption in elective spinal fusion patients.择期脊柱融合手术患者术前多模式镇痛可减少术后 24 小时阿片类药物用量。
Spine J. 2019 Nov;19(11):1753-1763. doi: 10.1016/j.spinee.2019.07.005. Epub 2019 Jul 17.
4
Major lower limb amputation audit - introduction and implementation of a multimodal perioperative pain management guideline.主要下肢截肢审计——多模式围手术期疼痛管理指南的介绍与实施
Br J Pain. 2018 Nov;12(4):257-258. doi: 10.1177/2049463718800736. Epub 2018 Sep 20.
5
Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial.围手术期给予选择性环氧化酶2抑制剂对膝关节置换术后疼痛管理和功能恢复的影响:一项随机对照试验
JAMA. 2003 Nov 12;290(18):2411-8. doi: 10.1001/jama.290.18.2411.
6
Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study.多模式镇痛可减少肩关节置换术后阿片类药物的消耗:一项前瞻性队列研究。
J Shoulder Elbow Surg. 2018 Apr;27(4):686-691. doi: 10.1016/j.jse.2017.11.015. Epub 2018 Jan 3.
7
Novel Multi-Modal Analgesia Protocol Significantly Decreases Opioid Requirements in Inflatable Penile Prosthesis Patients.新型多模式镇痛方案显著降低了可充气阴茎假体患者的阿片类药物需求。
J Sex Med. 2018 Aug;15(8):1187-1194. doi: 10.1016/j.jsxm.2018.05.017. Epub 2018 Jul 13.
8
Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery.围手术期持续静脉输注利多卡因用于术后疼痛与恢复。
Cochrane Database Syst Rev. 2015 Jul 16(7):CD009642. doi: 10.1002/14651858.CD009642.pub2.
9
The Addition of Diclofenac to a Multimodal Pain Control Regimen Decreases Postoperative Pain and Opioid Consumption.在多模式疼痛控制方案中添加双氯芬酸可减轻术后疼痛并减少阿片类药物的使用量。
Surg Technol Int. 2017 Dec 22;31:346-351.
10
Pain Management Using Perioperative Administration of Parecoxib for Total Hip Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.帕瑞昔布钠用于全髋关节置换术围手术期疼痛管理的随机、双盲、安慰剂对照试验。
Pain Physician. 2019 Nov;22(6):575-582.

引用本文的文献

1
Perioperative Pain Management for Major Limb Amputation - A Systematic-Narrative Hybrid Review.大肢体截肢围手术期疼痛管理——一项系统叙述性混合综述
Curr Pain Headache Rep. 2025 Mar 17;29(1):62. doi: 10.1007/s11916-025-01379-y.
2
Processes and approaches to perioperative pain management in patients undergoing major lower extremity amputations secondary to vascular disease: a multi-specialty modified Delphi consensus study protocol.血管疾病继发下肢大截肢患者围手术期疼痛管理的流程与方法:一项多专业改良德尔菲共识研究方案
BMJ Open. 2024 Dec 3;14(12):e090289. doi: 10.1136/bmjopen-2024-090289.
3
Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial.下肢大截肢后神经周围局部麻醉导管试验(PLACEMENT):一项随机对照可行性试验的结果。
BMJ Open. 2019 Nov 11;9(11):e029233. doi: 10.1136/bmjopen-2019-029233.
4
Major lower limb amputation audit - introduction and implementation of a multimodal perioperative pain management guideline.主要下肢截肢审计——多模式围手术期疼痛管理指南的介绍与实施
Br J Pain. 2018 Nov;12(4):257-258. doi: 10.1177/2049463718800736. Epub 2018 Sep 20.

本文引用的文献

1
Chronic post-amputation pain: peri-operative management - Review.慢性截肢后疼痛:围手术期管理——综述
Br J Pain. 2017 Nov;11(4):192-202. doi: 10.1177/2049463717736492. Epub 2017 Oct 9.
2
Improving the management of post-operative acute pain: priorities for change.改善术后急性疼痛管理:变革的优先事项。
Curr Med Res Opin. 2015 Nov;31(11):2131-43. doi: 10.1185/03007995.2015.1092122. Epub 2015 Sep 30.
3
Systematic review and meta-analysis of the efficacy of perineural local anaesthetic catheters after major lower limb amputation.系统评价和荟萃分析:大下肢截肢后神经周围局部麻醉导管的疗效。
Eur J Vasc Endovasc Surg. 2015 Aug;50(2):241-9. doi: 10.1016/j.ejvs.2015.04.030. Epub 2015 Jun 9.
4
The use of intravenous infusion or single dose of low-dose ketamine for postoperative analgesia: a review of the current literature.静脉输注或单剂量低剂量氯胺酮用于术后镇痛:当前文献综述
Pain Med. 2015 Feb;16(2):383-403. doi: 10.1111/pme.12619. Epub 2014 Dec 19.
5
Continuous regional anaesthesia provides effective pain management and reduces opioid requirement following major lower limb amputation.连续区域麻醉可提供有效的疼痛管理,并减少大下肢截肢术后阿片类药物的需求。
Eur J Vasc Endovasc Surg. 2014 Nov;48(5):559-64. doi: 10.1016/j.ejvs.2014.07.002. Epub 2014 Aug 16.
6
Perioperative gabapentinoids: choice of agent, dose, timing, and effects on chronic postsurgical pain.围手术期加巴喷丁类药物:药物选择、剂量、给药时间及对慢性术后疼痛的影响
Anesthesiology. 2013 Nov;119(5):1215-21. doi: 10.1097/ALN.0b013e3182a9a896.
7
Pharmacologic interventions for treating phantom limb pain.治疗幻肢痛的药物干预措施。
Cochrane Database Syst Rev. 2011 Dec 7(12):CD006380. doi: 10.1002/14651858.CD006380.pub2.
8
Continuous peripheral nerve blocks: a review of the published evidence.连续外周神经阻滞:已发表证据的综述。
Anesth Analg. 2011 Oct;113(4):904-25. doi: 10.1213/ANE.0b013e3182285e01. Epub 2011 Aug 4.
9
Lower extremity amputations--a review of global variability in incidence.下肢截肢术——全球发病率变化的综述。
Diabet Med. 2011 Oct;28(10):1144-53. doi: 10.1111/j.1464-5491.2011.03279.x.
10
Optimized perioperative analgesia reduces chronic phantom limb pain intensity, prevalence, and frequency: a prospective, randomized, clinical trial.优化围手术期镇痛可降低慢性幻肢痛的强度、发生率和频率:一项前瞻性、随机、临床试验。
Anesthesiology. 2011 May;114(5):1144-54. doi: 10.1097/ALN.0b013e31820fc7d2.

下肢大截肢审计——多模式围手术期疼痛管理指南的介绍与实施

Major lower limb amputation audit - introduction and implementation of a multimodal perioperative pain management guideline.

作者信息

Aladin Hafiz, Jennings Adrian, Hodges Max, Tameem Alifia

机构信息

Department of Anaesthetics, Dudley Group of Hospitals NHS Foundation Trust, Dudley, UK.

Department of Anaesthetics and Pain Management, Dudley Group of Hospitals NHS Foundation Trust, Dudley, UK.

出版信息

Br J Pain. 2018 Nov;12(4):230-237. doi: 10.1177/2049463718769339. Epub 2018 Apr 18.

DOI:10.1177/2049463718769339
PMID:30349697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6194968/
Abstract

Lower limb amputation is a frequent surgical intervention. It is well known to be associated with postoperative pain. Optimisation of perioperative pain has been shown to reduce the risk of chronic pain. There are no national guidelines for the perioperative pain management of lower limb amputations. Following a baseline audit, we devised a multimodal perioperative pain management guideline, which included the insertion of a local anaesthetic perineural catheter. All patients undergoing an elective or emergency above, through and below knee amputation were reviewed prior and following the implementation of this guideline. Patient postoperative pain scores and opiate usage were analysed. One hundred and twenty-four patients were reviewed (68 patients prior to the implementation of the guideline and 56 patients following the guideline introduction). Following the implementation of the guideline, a greater proportion of patient's pain scores were reported as 0 (i.e. no pain) compared to patients prior to its implementation (78% vs 61%). Pain scores were lower at all time intervals 6 days postoperatively following the guideline introduction. Statistically significant (Kendall's tau-b analysis) (p < 0.05) reduction in pain scores was found upon admission to the ward, 6, 12, 24 hours and 2 days postoperatively. Fewer patients required the use of opioid patient controlled of analgesia after the guideline was introduced (26% vs 4%). The implementation of a perioperative pain management guideline improved pain scores and reduced opioid consumption in patients undergoing lower limb amputations. We suggest a holistic and collaborative, multimodal pathway towards the perioperative pain management of lower limb amputations.

摘要

下肢截肢是一种常见的外科手术。众所周知,它与术后疼痛有关。已证明围手术期疼痛的优化可降低慢性疼痛的风险。目前尚无关于下肢截肢围手术期疼痛管理的国家指南。在进行基线审核后,我们制定了一项多模式围手术期疼痛管理指南,其中包括插入局部麻醉神经周围导管。对所有接受择期或急诊大腿、膝上、膝部及膝下截肢手术的患者在该指南实施前后进行了评估。分析了患者的术后疼痛评分和阿片类药物使用情况。共评估了124例患者(指南实施前68例,指南引入后56例)。与指南实施前的患者相比,指南实施后报告疼痛评分为0(即无疼痛)的患者比例更高(78%对61%)。指南引入后,术后6天内所有时间点的疼痛评分均较低。在入院时、术后6、12、24小时和2天,疼痛评分有统计学意义的降低(肯德尔tau-b分析)(p<0.05)。指南引入后,需要使用阿片类药物自控镇痛的患者减少(26%对4%)。围手术期疼痛管理指南的实施改善了下肢截肢患者的疼痛评分并减少了阿片类药物的消耗。我们建议采用一种全面、协作的多模式方法来进行下肢截肢的围手术期疼痛管理。