Wadhwa Vibhor
J Ark Med Soc. 2017 May;113(11):270-272.
ypophysitis is a reported compli- cation of ipilimumab, a monoclo- nal antibody which augments T- cell response against tumors. The imaging changes in the pituitary may precede or coincide with the hypopituitarism, but are frequently over- looked due to the subtle alteration in size and en- hancement characteristics. We present a series of 3 patients who developed hypophysitis and pituitary dysfunction subsequent to ipilimumab therapy and describe the MR imaging features and make follow up recommendations.
垂体炎是一种已报道的伊匹单抗（一种增强T细胞抗肿瘤反应的单克隆抗体）的并发症。垂体的影像学改变可能先于垂体功能减退出现或与之同时发生，但由于大小和强化特征的细微改变，这些改变常常被忽视。我们报告了3例在接受伊匹单抗治疗后发生垂体炎和垂体功能障碍的患者，并描述了其磁共振成像特征并提出随访建议。
