Rein Susanne, Hörnig Juliane, Houschyar Khosrow Siamak, Langwald Steffen, Hofmann Gunther, Siemers Frank
Klinikum Sankt Georg, Klinik für Plastische und Handchirurgie mit Schwerbrandverletztenzentrum.
Berufsgenossenschaftliche Klinik "Bergmannstrost" Klinik für Plastische und Handchirurgie, Brandverletztenzentrum.
Handchir Mikrochir Plast Chir. 2020 Apr;52(2):123-131. doi: 10.1055/a-0667-9794. Epub 2018 Oct 23.
The aim of this study was to analyse retrospectively the pre- and intraoperative factors influencing flap loss after free flap coverage of septic skin defects caused by osteitis of the lower extremity with an anterolateral thigh flap (ALT) or latissimus dorsi (LD) flap.
Twenty-seven patients were surgically treated with LD flap coverage and 45 patients with ALT flap coverage between 2004 and 2013. Their anthropometric, pre- and intraoperative parameters were investigated retrospectively.
Flap survival was 81.5 % for LD flaps and 82.2 % for ALT flaps. Major complications led to a significantly higher flap loss both in LD (p = 0.01) and ALT flaps (p < 0.0001). Furthermore, there was a significant increase in flap loss with pre-existing diabetes mellitus in the LD group (p = 0.001) and with acute osteomyelitis being the underlying cause of the soft tissue defect in the ALT group (p = 0.034). Regardless of the flap's postoperative success, LD flaps were used for significantly larger soft tissue defects to be reconstructed (p = 0.001), with the duration of surgery (p < 0.0001) and cold ischaemia time (p = 0.001) being significantly longer compared with ALT flaps.
The success of microsurgical flap reconstruction in lower extremities after osteitis was influenced by a low number of cases with preexisting diabetes mellitus, causative acute osteomyelitis, and major complications. Therefore, optimal management of both parameters and precise microsurgical anastomosis are prerequisites for successful plastic reconstruction of soft tissue defects.
本研究旨在回顾性分析采用股前外侧皮瓣(ALT)或背阔肌皮瓣(LD)游离皮瓣覆盖下肢骨髓炎所致感染性皮肤缺损术后皮瓣坏死的术前及术中影响因素。
回顾性调查2004年至2013年间接受LD皮瓣覆盖手术治疗的27例患者和接受ALT皮瓣覆盖手术治疗的45例患者的人体测量学、术前及术中参数。
LD皮瓣的皮瓣存活率为81.5%,ALT皮瓣为82.2%。主要并发症导致LD皮瓣(p = 0.01)和ALT皮瓣(p < 0.0001)的皮瓣坏死率显著更高。此外,LD组中,术前存在糖尿病会显著增加皮瓣坏死率(p = 0.001);ALT组中,急性骨髓炎作为软组织缺损的潜在病因会显著增加皮瓣坏死率(p = 0.034)。无论皮瓣术后是否成功,LD皮瓣用于重建的软组织缺损明显更大(p = 0.001),与ALT皮瓣相比,手术时间(p < 0.0001)和冷缺血时间(p = 0.001)显著更长。
骨髓炎后下肢显微外科皮瓣重建的成功受到术前存在糖尿病、病因性急性骨髓炎和主要并发症病例数较少的影响。因此,对这些参数进行优化管理以及精确的显微外科吻合是软组织缺损成功整形重建的先决条件。