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全腔内血管修复术后主动脉重塑:3 年随访期间主动脉重塑的计算流体动力学分析。

Aortic Remodeling After Total Endovascular Aortic Repair With Multilayer Stents: Computational Fluid Dynamics Analysis of Aortic Remodeling Over 3 Years of Follow-up.

机构信息

1 NextCardio Project ULBS, Lucian Blaga University, Sibiu, Romania.

2 Department of Vascular Surgery, Amsterdam University Medical Center, Amsterdam, the Netherlands.

出版信息

J Endovasc Ther. 2018 Dec;25(6):760-764. doi: 10.1177/1526602818808049. Epub 2018 Oct 24.

Abstract

PURPOSE

To report Multilayer Flow Modulator (MFM) implantation from the sinotubular junction to the distal infrarenal aorta in the treatment of type B aortic dissection (TBAD) and demonstrate aortic remodeling using computational fluid dynamics (CFD) analysis over the course of 3-year follow-up.

CASE REPORT

A hypertensive patient with complicated TBAD required thoracic endovascular aortic repair due to severe thoracic pain associated with rapid progression of the false lumen aneurysm toward the distal aortic arch. Under general anesthesia, 2 aortic multilayer stents were placed over a 0.035-inch stiff guidewire in the compressed true lumen. The aorta was covered with 2 MFM stents between the sinotubular junction and the distal infrarenal aorta. Serial computed tomography scans showed progressive remodeling of the entire dissected aortic wall, with an excellent result at 24 months. Morphological and CFD vascular analysis confirmed the aortic remodeling, with a false lumen index drop from a preoperative 4.04 to 0.01 at 36 months.

CONCLUSION

Endovascular aortic repair with multilayer stents is a promising treatment for complicated TBAD due to the unique ability of these devices to stabilize the entire aortic wall without compromising the flow in the major aortic side branches.

摘要

目的

报告从窦管交界处到远端肾下主动脉的多层流调节器(MFM)植入术治疗 B 型主动脉夹层(TBAD)的情况,并在 3 年的随访中通过计算流体动力学(CFD)分析来展示主动脉重塑情况。

病例报告

一名高血压合并复杂 TBAD 的患者因胸痛严重且假腔动脉瘤迅速向远端主动脉弓进展,需要进行胸主动脉腔内修复术。在全身麻醉下,使用 0.035 英寸硬导丝在压缩的真腔内放置 2 个主动脉多层支架。在窦管交界处和远端肾下主动脉之间放置 2 个 MFM 支架覆盖整个主动脉。连续的计算机断层扫描显示整个夹层主动脉壁的进行性重塑,24 个月时结果非常好。形态学和 CFD 血管分析证实了主动脉重塑,假腔指数从术前的 4.04 降至 36 个月时的 0.01。

结论

对于复杂 TBAD,使用多层支架的血管内修复术是一种有前途的治疗方法,因为这些设备具有稳定整个主动脉壁的独特能力,而不会影响主要主动脉侧支的血流。

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