Transplantation Unit, Department of Surgery, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel.
Division of Transplant Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-4283, USA; email:
Annu Rev Med. 2019 Jan 27;70:225-238. doi: 10.1146/annurev-med-051517-125454. Epub 2018 Oct 24.
Adult-to-adult living donor liver transplantation (LDLT) was introduced in response to the shortage of deceased donor liver grafts. The number of adult living donor transplants is increasing due to improved outcomes and increasing need. Advantages of LDLT include optimization of the timing of transplant, better organ quality, and lower rates of recipient mortality compared to staying on the wait list for deceased donor liver transplant. Donor safety remains the major focus when considering LDLT. Recent advancements have supported the increased use of LDLT to help decrease wait list death and improve long-term survival of transplant recipients.
成人对成人活体肝移植（LDLT）的引入是为了应对已故供体肝脏供体的短缺。由于结果改善和需求增加，成人活体供肝移植的数量正在增加。与等待已故供体肝移植相比，LDLT 的优势包括可优化移植时机、改善供体器官质量和降低受体死亡率。在考虑 LDLT 时，供体安全仍然是主要关注点。最近的进展支持增加 LDLT 的使用，以帮助减少等待名单上的死亡人数，并提高移植受者的长期生存率。
