某转诊医院所有员工潜伏性结核感染的流行率及相关因素。

Prevalence of and factors related to latent tuberculous infection among all employees in a referral hospital.

机构信息

Division of Pulmonary Medicine, Department of Internal Medicine, Hallym University Hangang Sacred Heart Hospital, Seoul.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul.

出版信息

Int J Tuberc Lung Dis. 2018 Nov 1;22(11):1329-1335. doi: 10.5588/ijtld.18.0047.

DOI:10.5588/ijtld.18.0047

PMID:30355413

Abstract

SETTING

Referral hospital, South Korea.

OBJECTIVE

To investigate the prevalence of and factors related to latent tuberculous infection (LTBI) among all hospital employees.

DESIGN

A cross-sectional study of 479 health care workers (HCWs) undergoing LTBI screening.

RESULTS

Overall prevalence of LTBI was 15.7%, 43.1% of whom initiated and completed LTBI treatment. Compared with HCWs without LTBI, those with LTBI were more likely to be older ( < 0.001), male ( = 0.003), work in low-risk departments ( = 0.013) and have more years of employment ( < 0.001). LTBI prevalence was highest in physicians (27.8%), followed by HCWs without patient contact (23.4%), nurses (8.3%) and other HCWs in contact with patients (6.9%). In multivariate analysis, compared with HCWs aged <20 years, those aged 40 years were 4.08 times more likely to have LTBI ( = 0.007). In addition, compared with HCWs working for <1 year, those working for 1-5 years or for 5 years were respectively 7.55 ( = 0.014) and 13.69 ( = 0.001) times more likely to have LTBI.

CONCLUSIONS

Our results suggest that modified LTBI screening strategies, including HCWs with no patient contact and encouraging LTBI treatment participation, might be helpful in improving LTBI control in HCWs.

摘要

背景

转诊医院，韩国。

目的

调查所有医院员工中潜伏性结核感染（LTBI）的流行情况和相关因素。

设计

对 479 名接受 LTBI 筛查的卫生保健工作者（HCWs）进行的横断面研究。

结果

总体 LTBI 患病率为 15.7%，其中 43.1%的人开始并完成了 LTBI 治疗。与无 LTBI 的 HCWs 相比，LTBI 患者更可能年龄较大（<0.001）、男性（=0.003）、工作在低风险科室（=0.013）和工作年限较长（<0.001）。LTBI 患病率以医生最高（27.8%），其次是非接触患者的 HCWs（23.4%）、护士（8.3%）和接触患者的其他 HCWs（6.9%）。多变量分析显示，与年龄<20 岁的 HCWs 相比，年龄≥40 岁的 HCWs 发生 LTBI 的可能性高 4.08 倍（=0.007）。此外，与工作年限<1 年的 HCWs 相比，工作年限为 1-5 年或≥5 年的 HCWs 发生 LTBI 的可能性分别高 7.55 倍（=0.014）和 13.69 倍（=0.001）。