Wardani Hamidah Retno, Mertaniasih Ni Made, Soedarsono Soedarsono
Student of Master Program of Tropical Medicine, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen. Prof. Dr. Moestopo No. 47, Surabaya 60131, Indonesia.
Department of Clinical Microbiology, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen. Prof. Dr. Moestopo No. 47, Surabaya 60131, Indonesia.
Afr J Infect Dis. 2020 Dec 14;15(1):34-40. doi: 10.21010/ajid.v15i1.4. eCollection 2021.
Healthcare workers in Tuberculosis (TB) and non-TB units in hospitals have a high risk of experiencing Latent Tuberculosis Infection (LTBI), because of exposure to droplets containing . This study aims to prove LTBI incidence and risk factors to healthcare workers at the hospital in Jember City.
a cross-sectional study, from January to March 2020 in two hospitals in Jember City. Healthcare workers in the TB care and non-TB care unit were examined using Tuberculin skin test (TST) with a cut off ≥ 10 mm for positive LTBI. Chest x-ray and clinical examination to rule out active TB and a standardized questionnaire were also used.
128 healthcare workers completed the questionnaires, clinical, tuberculin skin test (TST), and chest x-ray data. LTBI incidence of positive results 61.7% (n = 79). Contacts TB in the workplace (p value = 0.219; OR = 1.643; CI = 0.742-3.641) and a unit of work (p value = 0.102; OR = 0.760; CI = 0.559-1.031) has no relationship with LTBI. The profession (p value = 0.020; OR = 1.112; CI = 0.896-1.403), the duration of the work (p value = 0.039; OR = 2.984; CI = 1.067-8.342), and BCG immunization (p value =0.000; OR = 0.151; CI = 0.052-0.438) have important relationships with LTBI.
TB infection with a high incidence, a risk of transmission to healthcare workers, and a relationship between occupational risk factors and LTBI among healthcare workers in Jember City, Indonesia have been established in this study.
由于接触含有结核菌的飞沫，医院结核病（TB）科室和非结核病科室的医护人员发生潜伏性结核感染（LTBI）的风险很高。本研究旨在证实印度尼西亚任抹市医院医护人员的LTBI发病率及其危险因素。
2020年1月至3月在任抹市的两家医院开展一项横断面研究。对结核病护理科室和非结核病护理科室的医护人员采用结核菌素皮肤试验（TST）进行检测，LTBI阳性的截断值为≥10毫米。同时还进行胸部X光检查和临床检查以排除活动性结核病，并使用标准化问卷进行调查。
128名医护人员完成了问卷调查、临床检查、结核菌素皮肤试验（TST）及胸部X光检查。LTBI检测结果阳性率为61.7%（n = 79）。在工作场所接触结核病患者（p值 = 0.219；比值比[OR] = 1.643；可信区间[CI] = 0.742 - 3.641）以及工作科室（p值 = 0.102；OR = 0.760；CI = 0.559 - 1.031）与LTBI均无关联。职业（p值 = 0.020；OR = 1.112；CI = 0.896 - 1.403）、工作时长（p值 = 0.039；OR = 2.984；CI = 1.067 - 8.342）和卡介苗免疫接种（p值 = 0.000；OR = 0.151；CI = 0.052 - 0.438）与LTBI存在重要关联。
本研究证实了印度尼西亚任抹市医院医护人员中结核病感染率高、存在传染给医护人员的风险以及职业危险因素与LTBI之间存在关联。
