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瑞典丹德吕德大学医院由医院急救团队进行的院内心脏骤停复苏:一项6年的回顾性登记分析

In-hospital cardiac arrest resuscitation performed by the hospital emergency team: A 6-year retrospective register analysis at Danderyd University Hospital, Sweden.

作者信息

Widestedt Hedwig, Giesecke Jasna, Karlsson Pernilla, Jakobsson Jan G

机构信息

Department of Anaesthesia & Intensive Care, Institution for Clinical Sciences, Danderyds University Hospital, Karolinska Institutet, Stockholm, 182 88, Sweden.

Clinicum- Centre for Clinical Skills, Interprofessional Education and Advanced Medical Simulation, Danderyds University Hospital, Stockholm, 182 88, Sweden.

出版信息

F1000Res. 2018 Jul 6;7:1013. doi: 10.12688/f1000research.15373.1. eCollection 2018.

Abstract

Cardiac arrest requires rapid and effective handling. Huge efforts have been implemented to improve resuscitation of sudden cardiac arrest patients. Guidelines around the various parts of effective management, the , are available. The aim of the present retrospective study was to study sudden in-hospital cardiac arrest (IHCA) and the outcomes of emergence team resuscitation in a university hospital in Sweden. The Swedish Cardiopulmonary Resuscitation Registry was used to access all reported cases of IHCA at Danderyd Hospital from 2012 through 2017. Return of spontaneous circulation (ROSC), discharge alive, 30-day mortality and Cerebral Performance Scales score (CPC) were analysed. 574 patients with cardiac arrests were included in the study: 307 patients (54%) had ROSC; 195 patients (34%) were alive to be discharged from hospital; and 191 patients (33%) were still alive at day-30 after cardiac arrest. Witnessed cardiac arrests, VT/VF as initial rhythm and experiencing cardiac arrest in high monitored wards were factors associated with success. However, 53% of patients' alive at day-30 had a none-shockable rhythm, 16% showed initially a pulseless electrical activity and 37% asystole. CPC score was available for 188 out of the 195 patients that were alive to be discharged: 96.5% of patients where data was available had a favourable neurological outcome, a CPC-score of 1 or 2 at discharge, and only 6 of these patients had a CPC-score of 3 or higher (3%). One third of patients with sudden IHCA were discharged from hospital and alive at day-30, a clear majority without cognitive deficit related to the cardiac arrest. High monitored care, witnessed cardiac arrest and shockable rhythm were factors associated with high success; however, more than half of surviving patients had initially a none-shockable rhythm.

摘要

心脏骤停需要迅速且有效的处理。人们已经付出巨大努力来改善心脏骤停患者的复苏情况。关于有效管理各个环节的指南已经出台。本回顾性研究的目的是研究瑞典一家大学医院内发生的院内心脏骤停(IHCA)以及急诊团队复苏的结果。瑞典心肺复苏登记处用于获取2012年至2017年丹德吕德医院所有报告的院内心脏骤停病例。分析自主循环恢复(ROSC)、出院存活情况、30天死亡率和脑功能评分(CPC)。574例心脏骤停患者纳入研究:307例患者(54%)实现自主循环恢复;195例患者(34%)存活至出院;191例患者(33%)在心脏骤停后30天仍存活。目击心脏骤停、初始心律为室性心动过速/心室颤动以及在高监测病房发生心脏骤停是与成功相关的因素。然而,30天存活的患者中有53%的初始心律不可电击,16%最初表现为无脉电活动,37%为心脏停搏。195例存活至出院的患者中有188例有脑功能评分:在有数据的患者中,96.5%有良好的神经学转归,出院时脑功能评分为1或2,其中只有6例患者脑功能评分为3或更高(3%)。三分之一的院内心脏骤停患者出院且在30天存活,绝大多数患者没有与心脏骤停相关的认知缺陷。高监测护理、目击心脏骤停和可电击心律是与高成功率相关的因素;然而,超过一半的存活患者初始心律不可电击。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3126/6178903/91b389554a37/f1000research-7-16752-g0000.jpg

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