Department of Radiology, Neuroradiology Section, Stanford University School of Medicine, Palo Alto, CA.
Department of Neurology, PLA Army General Hospital, Beijing, China.
J Neuroimaging. 2019 Jan;29(1):119-125. doi: 10.1111/jon.12573. Epub 2018 Oct 25.
To characterize the relationship between computed tomography angiography (CTA) imaging characteristics of carotid artery and the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) score.
We retrospectively identified all patients who underwent a cervical CTA at our institution from January 2013 to July 2016, extracted clinical information, and calculated the 10-year ASCVD score using the Pooled Cohort Equations from the 2013 ACC/AHA guidelines. We compared the imaging features of artery atherosclerosis derived from the CTAs between low and high risk.
One hundred forty-six patients met our inclusion criteria. Patients with an ASCVD score ≥7.5% (64.4%) had significantly more arterial stenosis than patients with an ASCVD score <7.5% (35.6%, P < .001). Maximal plaque thickness was significantly higher (mean 2.33 vs. .42 mm, P < .001) and soft plaques (55.3% vs. 13.5%, P < .001) were significantly more frequent in patients with an ASCVD score ≥7.5%. However, among patients with a 10-year ASCVD score ≥7.5%, 33 (35.1%) had no arterial stenosis, 35 (37.2%) had a maximal plaque thickness less than. 9 mm, and 42 (44.7%) had no soft plaque. Furthermore, among the patients with a 10-year ASCVD score <7.5%, 8 (15.4%) had some arterial stenosis, 8 (15.4%) had a maximal plaque thickness more than. 9 mm, and 7 (13.5%) had soft plaque.
There is some concordance but not a perfect overlap between the 10-year ASCVD risk scores calculated from clinical and blood assessment and carotid artery imaging findings.
描述颈动脉计算机断层血管造影（CTA）影像学特征与 10 年动脉粥样硬化性心血管疾病（ASCVD）风险评分之间的关系。
我们回顾性地从 2013 年 1 月至 2016 年 7 月在我们机构进行颈 CTA 的所有患者中提取临床信息，并使用 2013 年 ACC/AHA 指南中的汇总队列方程计算 10 年 ASCVD 评分。我们比较了低风险和高风险患者 CTA 得出的动脉粥样硬化影像学特征。
符合纳入标准的患者共 146 例。ASCVD 评分≥7.5%（64.4%）的患者动脉狭窄程度明显高于 ASCVD 评分<7.5%（35.6%）的患者（P<.001）。最大斑块厚度明显较高（平均值 2.33mm 比.42mm，P<.001），且软斑块（55.3%比 13.5%，P<.001）在 ASCVD 评分≥7.5%的患者中更为常见。然而，在 ASCVD 评分≥7.5%的患者中，有 33 例（35.1%）无动脉狭窄，35 例（37.2%）最大斑块厚度<0.9mm，42 例（44.7%）无软斑块。此外，在 ASCVD 评分<7.5%的患者中，有 8 例（15.4%）有一些动脉狭窄，8 例（15.4%）最大斑块厚度>0.9mm，7 例（13.5%）有软斑块。
从临床和血液评估以及颈动脉影像学检查得出的 10 年 ASCVD 风险评分之间存在一定的一致性，但并不完全重叠。
