Zhang Song, Wang Zhen, Yao Yao, Li Junfei
Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092.
Shanghai MicroPort Co. Ltd., Shanghai, 201203.
Zhongguo Yi Liao Qi Xie Za Zhi. 2018 Sep 30;42(5):335-338. doi: 10.3969/j.issn.1671-7104.2018.05.007.
Atrial fibrillation (AF) is one of the most common arrhythmia in clinic. Left atrial appendage closure is a new technique developed to block the left atrial appendage by minimally invasive intervention in patients with atrial fibrillation, it can help patients who are not applicable or tolerable to the long-term anticoagulation. This paper introduced the common classification of left atrial appendage, summarized and analyzed the limitation of existing left atrial appendage closure. Based on the perspective of clinical needs, it put forward the initial design idea of left atrial appendage closure and designed a new type of left atrial appendage closure. Corresponding animal experiment verified the safety and effectiveness of new left atrial appendage closure.
心房颤动（AF）是临床上最常见的心律失常之一。左心耳封堵术是一种通过微创介入封堵左心耳而开发的新技术，适用于房颤患者，可帮助那些不适合或不耐受长期抗凝治疗的患者。本文介绍了左心耳的常见分类，总结并分析了现有左心耳封堵术的局限性。基于临床需求的视角，提出了左心耳封堵术的初步设计思路，并设计了一种新型左心耳封堵器。相应的动物实验验证了新型左心耳封堵器的安全性和有效性。
