Goldman A, Staub H, Wollina U
Clinica Goldman and Hospital Moinhos de Vento, Porto Alegre; Department of Rheumatology, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil; Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital of the Technical University of Dresden, Germany.
Georgian Med News. 2018 Sep(282):17-20.
Hypercalcemia is a common feature of malignancy, bone metabolic conditions and granulomatous disorders. In the latter, hypercalcemia is usually calcitriol-related. As eventual association of silicone and polymethylmethacrylate (PMMA) injections with granulomatous disease and hypercalcemia the condition has become an issue of recent interest. Authors report on two cases of calcitriol-related hypercalcemia where PMMA injections had been previously administered. The association, even though intriguing, requires additional confirmation by follow-up studies.
高钙血症是恶性肿瘤、骨代谢疾病和肉芽肿性疾病的常见特征。在后者中,高钙血症通常与骨化三醇有关。由于硅酮和聚甲基丙烯酸甲酯(PMMA)注射最终与肉芽肿性疾病和高钙血症相关联,这种情况已成为近期关注的一个问题。作者报告了两例先前曾接受过PMMA注射的与骨化三醇相关的高钙血症病例。这种关联尽管很有趣,但需要后续研究进一步证实。