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二手暴露于电子烟气溶胶与青少年哮喘哮喘恶化的关系。

Secondhand Exposure to Aerosols From Electronic Nicotine Delivery Systems and Asthma Exacerbations Among Youth With Asthma.

机构信息

Division of Intramural Research, National Institute on Minority Health and Health Disparities, Bethesda, MD.

Department of Epidemiology and Biostatistics, George Washington University, Washington, DC.

出版信息

Chest. 2019 Jan;155(1):88-93. doi: 10.1016/j.chest.2018.10.005. Epub 2018 Oct 22.

Abstract

BACKGROUND

Current research suggests an association between the use of electronic nicotine delivery systems (ENDS) and asthma symptoms in youth, but little is known about the association of secondhand ENDS aerosol exposure and asthma control. The present study examines the relationship of secondhand ENDS aerosol exposure and asthma exacerbations among youth with asthma.

METHODS

Youth who participated in the 2016 Florida Youth Tobacco survey (aged 11-17 years) with a self-reported diagnosis of asthma (N = 11,830) reported asthma attacks in the past 12 months, demographic characteristics, cigarette use, cigar use, hookah use, ENDS use, past 30-day secondhand smoke exposure, and past 30-day secondhand ENDS aerosol exposure. Weighted multivariable logistic regression models were used to examine the association between secondhand ENDS aerosol exposure and past 12-month asthma attack status, adjusting for covariates.

RESULTS

Overall, 21% of youth with asthma reported having an asthma attack in the past 12 months, and 33% reported secondhand ENDS aerosol exposure. Secondhand ENDS aerosol exposure was associated with higher odds of reporting an asthma attack in the past 12 months, adjusting for covariates (adjusted OR, 1.27; 95% CI, 1.11-1.47).

CONCLUSIONS

Secondhand exposure to ENDS aerosols may be related to asthma symptoms in youth. Physicians may need to counsel youth with asthma regarding the potential risks of exposure. Future research is necessary to evaluate the longitudinal relationship between secondhand ENDS aerosol exposure and asthma control.

摘要

背景

目前的研究表明,青少年使用电子尼古丁传送系统(ENDS)与哮喘症状之间存在关联,但对于二手 ENDS 气溶胶暴露与哮喘控制之间的关联知之甚少。本研究探讨了二手 ENDS 气溶胶暴露与哮喘青少年哮喘加重之间的关系。

方法

参加 2016 年佛罗里达青少年烟草调查(年龄在 11-17 岁)且自我报告患有哮喘的青少年(N=11830)报告了过去 12 个月内的哮喘发作、人口统计学特征、香烟使用、雪茄使用、水烟使用、ENDS 使用、过去 30 天二手烟暴露和过去 30 天二手 ENDS 气溶胶暴露。使用加权多变量逻辑回归模型,在调整协变量的情况下,检验二手 ENDS 气溶胶暴露与过去 12 个月哮喘发作状态之间的关联。

结果

总体而言,21%的哮喘青少年报告过去 12 个月内有哮喘发作,33%报告二手 ENDS 气溶胶暴露。在调整协变量后,二手 ENDS 气溶胶暴露与过去 12 个月内报告哮喘发作的几率较高相关(调整后的比值比,1.27;95%可信区间,1.11-1.47)。

结论

二手接触 ENDS 气溶胶可能与青少年哮喘症状有关。医生可能需要就暴露的潜在风险向哮喘青少年提供咨询。需要进一步研究来评估二手 ENDS 气溶胶暴露与哮喘控制之间的纵向关系。

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