• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
An Infertile Couple's Long and Expensive Path to Varicocele Repair.一对不孕夫妇进行精索静脉曲张修复的漫长而昂贵之路。
Urology. 2019 Feb;124:131-135. doi: 10.1016/j.urology.2018.10.021. Epub 2018 Oct 23.
2
Microsurgical varicocelectomy for infertile couples with advanced female age: natural history in the era of ART.针对高龄女性不孕夫妇的显微外科精索静脉曲张切除术:辅助生殖技术时代的自然病程
J Androl. 2004 Nov-Dec;25(6):939-43. doi: 10.1002/j.1939-4640.2004.tb03165.x.
3
Undergoing varicocele repair before assisted reproduction improves pregnancy rate and live birth rate in azoospermic and oligospermic men with a varicocele: a systematic review and meta-analysis.在辅助生殖前进行精索静脉曲张修复可提高患有精索静脉曲张的无精子症和少精子症男性的妊娠率和活产率:一项系统评价和荟萃分析。
Fertil Steril. 2016 Nov;106(6):1338-1343. doi: 10.1016/j.fertnstert.2016.07.1093. Epub 2016 Aug 12.
4
Natural history of varicocele management in the era of intracytoplasmic sperm injection.卵胞浆内单精子注射时代精索静脉曲张治疗的自然史
Fertil Steril. 2008 Dec;90(6):2251-6. doi: 10.1016/j.fertnstert.2007.10.071. Epub 2008 Jan 28.
5
Varicocelectomy to "upgrade" semen quality to allow couples to use less invasive forms of assisted reproductive technology.精索静脉曲张切除术可“提升”精液质量,使夫妻能够采用侵入性较小的辅助生殖技术形式。
Fertil Steril. 2017 Oct;108(4):609-612. doi: 10.1016/j.fertnstert.2017.07.017. Epub 2017 Sep 11.
6
Varicocele repair for infertility: what is the evidence?精索静脉曲张修复治疗不育症:有何证据?
Curr Opin Urol. 2012 Nov;22(6):489-94. doi: 10.1097/MOU.0b013e328358e115.
7
Decisional Conflict and Knowledge Among Patients With Varicocele Seeking Treatment for Infertility.精索静脉曲张致不孕患者治疗意愿的决策冲突与知识。
Urology. 2020 Aug;142:112-118. doi: 10.1016/j.urology.2020.05.014. Epub 2020 May 20.
8
Left spermatic vein reflux after varicocele repair predicts pregnancies and live births in subfertile couples.精索静脉修复术后左侧精索静脉反流可预测不孕夫妇的妊娠和活产。
J Endocrinol Invest. 2019 Oct;42(10):1215-1221. doi: 10.1007/s40618-019-01042-5. Epub 2019 Apr 6.
9
Relationship of varicocele to sperm output and fertility of male partners in infertile couples.精索静脉曲张与不育夫妇男性伴侣精子产量及生育力的关系。
J Urol. 1978 Dec;120(6):691-4. doi: 10.1016/s0022-5347(17)57332-2.
10
Surgery or embolization for varicoceles in subfertile men.对不育男性精索静脉曲张进行手术或栓塞治疗。
Cochrane Database Syst Rev. 2012 Oct 17;10:CD000479. doi: 10.1002/14651858.CD000479.pub5.

引用本文的文献

1
Jiawei Runjing Decoction Improves Spermatogenesis of Cryptozoospermia With Varicocele by Regulating the Testicular Microenvironment: Two-Center Prospective Cohort Study.加味润精汤通过调节睾丸微环境改善精索静脉曲张性隐匿精子症的精子发生:双中心前瞻性队列研究
Front Pharmacol. 2022 Aug 9;13:945949. doi: 10.3389/fphar.2022.945949. eCollection 2022.

本文引用的文献

1
The Impact of Microsurgical Repair of Subclinical and Clinical Varicoceles on Total Motile Sperm Count: Is There a Difference?亚临床型和临床型精索静脉曲张显微外科修复对总活动精子计数的影响:有差异吗?
Urology. 2018 Oct;120:109-113. doi: 10.1016/j.urology.2018.06.036. Epub 2018 Jul 5.
2
Changes in practice patterns in male infertility cases in the United States: the trend toward subspecialization.美国男性不育症病例实践模式的变化:向亚专科分化的趋势。
Fertil Steril. 2018 Jul 1;110(1):76-82. doi: 10.1016/j.fertnstert.2018.03.020.
3
Prediction of male infertility by the World Health Organization laboratory manual for assessment of semen analysis: A systematic review.世界卫生组织精液分析评估实验室手册对男性不育症的预测:一项系统综述。
Arab J Urol. 2017 Nov 20;16(1):96-102. doi: 10.1016/j.aju.2017.10.005. eCollection 2018 Mar.
4
Varicocelectomy to "upgrade" semen quality to allow couples to use less invasive forms of assisted reproductive technology.精索静脉曲张切除术可“提升”精液质量,使夫妻能够采用侵入性较小的辅助生殖技术形式。
Fertil Steril. 2017 Oct;108(4):609-612. doi: 10.1016/j.fertnstert.2017.07.017. Epub 2017 Sep 11.
5
Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios.精子DNA碎片检测的临床应用:基于临床场景的实践建议
Transl Androl Urol. 2016 Dec;5(6):935-950. doi: 10.21037/tau.2016.10.03.
6
The significance of clinical practice guidelines on adult varicocele detection and management.成人精索静脉曲张检测与管理临床实践指南的意义
Asian J Androl. 2016 Mar-Apr;18(2):269-75. doi: 10.4103/1008-682X.172641.
7
Epidemiology of varicocele.精索静脉曲张的流行病学
Asian J Androl. 2016 Mar-Apr;18(2):179-81. doi: 10.4103/1008-682X.172640.
8
Trends of male factor infertility, an important cause of infertility: A review of literature.男性因素不孕症的趋势——不孕症的一个重要原因:文献综述
J Hum Reprod Sci. 2015 Oct-Dec;8(4):191-6. doi: 10.4103/0974-1208.170370.
9
Practice patterns in the surgical approach for adolescent varicocelectomy.青少年精索静脉曲张切除术的手术方法实践模式
Springerplus. 2015 Dec 14;4:772. doi: 10.1186/s40064-015-1573-7. eCollection 2015.
10
Proteomic profile of seminal plasma in adolescents and adults with treated and untreated varicocele.患有经治疗和未经治疗的精索静脉曲张的青少年和成年人精浆的蛋白质组学特征
Asian J Androl. 2016 Mar-Apr;18(2):194-201. doi: 10.4103/1008-682X.168788.

一对不孕夫妇进行精索静脉曲张修复的漫长而昂贵之路。

An Infertile Couple's Long and Expensive Path to Varicocele Repair.

作者信息

Balasubramanian Adithya, Thirumavalavan Nannan, Scovell Jason M, Lo Jonathan, Ji Byung, Godfrey Elizabeth L, Pastuszak Alexander W, Lipshultz Larry I

机构信息

Center for Reproductive Medicine, Scott Department of Urology, Baylor College of Medicine, Houston, TX.

Center for Reproductive Medicine, Scott Department of Urology, Baylor College of Medicine, Houston, TX.

出版信息

Urology. 2019 Feb;124:131-135. doi: 10.1016/j.urology.2018.10.021. Epub 2018 Oct 23.

DOI:10.1016/j.urology.2018.10.021
PMID:30359710
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6387868/
Abstract

OBJECTIVE

To characterize the pathways to care that infertile couples requiring varicocele repair (VR) pursue prior to presenting to a male fertility clinic.

METHODS

An IRB-approved single center retrospective review of patients undergoing VR after presentation to an academic male fertility clinic was performed. Patients whose charts included partner histories were assessed for duration of attempting conception, prior workup, and assisted reproductive technology (ART) use.

RESULTS

A total of 405 couples were included. At presentation, mean age was 34.4 (SD ± 6.5) years for men and 31.1 (SD ± 4.3) years for women (P < .0001). A couple's first visit to a physician was a gynecologist in 59% (198/334) of couples, a reproductive endocrinologist (REI) in 25% (83/334) of cases, with 14% (47/334) presenting without a previous female workup and were self-referred, and 2% (6/334) seeing both a gynecologist and REI prior to presentation. On average, couples attempted pregnancy for 22.3 (SD ± 21.1, range 0-120) months prior to presentation. Eighteen percent of couples underwent ART prior to presentation. Couples who had undergone ART had lower pre-VR total motile sperm counts compared to couples not pursuing ART prior to presentation (P = 0.031). The majority (70.4%) of females had no abnormality in their workup, making varicocele the only correctable factor for infertility in the couple.

CONCLUSIONS

Our findings show a significant delay in referral of infertile men requiring VR. Eighteen percent of couples underwent costly ART prior to an inexpensive male workup. In an era of medical cost containment, early referral to a male infertility specialist is imperative.

摘要

目的

描述需要进行精索静脉曲张修复术(VR)的不孕夫妇在前往男性生育诊所就诊之前所采取的就医途径。

方法

对在一家学术性男性生育诊所就诊后接受VR的患者进行了一项经机构审查委员会批准的单中心回顾性研究。对病历中包含配偶病史的患者,评估其尝试受孕的时间、先前的检查以及辅助生殖技术(ART)的使用情况。

结果

共纳入405对夫妇。就诊时,男性的平均年龄为34.4(标准差±6.5)岁,女性为31.1(标准差±4.3)岁(P <.0001)。59%(198/334)的夫妇首次就诊医生是妇科医生,25%(83/334)的病例是生殖内分泌学家(REI),14%(47/334)的夫妇未经过先前的女性检查而是自行转诊,2%(6/334)的夫妇在就诊前同时看过妇科医生和REI。平均而言,夫妇在就诊前尝试怀孕22.3(标准差±21.1,范围0 - 120)个月。18%的夫妇在就诊前接受了ART。与就诊前未进行ART的夫妇相比,接受过ART的夫妇在VR前的总活动精子计数较低(P = 0.031)。大多数(70.4%)女性的检查无异常,使精索静脉曲张成为这对夫妇不孕的唯一可纠正因素。

结论

我们的研究结果显示,需要VR的不孕男性转诊存在显著延迟。18%的夫妇在进行费用低廉的男性检查之前就接受了昂贵的ART。在医疗费用控制的时代,尽早转诊至男性不育专家处至关重要。