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一对不孕夫妇进行精索静脉曲张修复的漫长而昂贵之路。

An Infertile Couple's Long and Expensive Path to Varicocele Repair.

作者信息

Balasubramanian Adithya, Thirumavalavan Nannan, Scovell Jason M, Lo Jonathan, Ji Byung, Godfrey Elizabeth L, Pastuszak Alexander W, Lipshultz Larry I

机构信息

Center for Reproductive Medicine, Scott Department of Urology, Baylor College of Medicine, Houston, TX.

Center for Reproductive Medicine, Scott Department of Urology, Baylor College of Medicine, Houston, TX.

出版信息

Urology. 2019 Feb;124:131-135. doi: 10.1016/j.urology.2018.10.021. Epub 2018 Oct 23.

Abstract

OBJECTIVE

To characterize the pathways to care that infertile couples requiring varicocele repair (VR) pursue prior to presenting to a male fertility clinic.

METHODS

An IRB-approved single center retrospective review of patients undergoing VR after presentation to an academic male fertility clinic was performed. Patients whose charts included partner histories were assessed for duration of attempting conception, prior workup, and assisted reproductive technology (ART) use.

RESULTS

A total of 405 couples were included. At presentation, mean age was 34.4 (SD ± 6.5) years for men and 31.1 (SD ± 4.3) years for women (P < .0001). A couple's first visit to a physician was a gynecologist in 59% (198/334) of couples, a reproductive endocrinologist (REI) in 25% (83/334) of cases, with 14% (47/334) presenting without a previous female workup and were self-referred, and 2% (6/334) seeing both a gynecologist and REI prior to presentation. On average, couples attempted pregnancy for 22.3 (SD ± 21.1, range 0-120) months prior to presentation. Eighteen percent of couples underwent ART prior to presentation. Couples who had undergone ART had lower pre-VR total motile sperm counts compared to couples not pursuing ART prior to presentation (P = 0.031). The majority (70.4%) of females had no abnormality in their workup, making varicocele the only correctable factor for infertility in the couple.

CONCLUSIONS

Our findings show a significant delay in referral of infertile men requiring VR. Eighteen percent of couples underwent costly ART prior to an inexpensive male workup. In an era of medical cost containment, early referral to a male infertility specialist is imperative.

摘要

目的

描述需要进行精索静脉曲张修复术(VR)的不孕夫妇在前往男性生育诊所就诊之前所采取的就医途径。

方法

对在一家学术性男性生育诊所就诊后接受VR的患者进行了一项经机构审查委员会批准的单中心回顾性研究。对病历中包含配偶病史的患者,评估其尝试受孕的时间、先前的检查以及辅助生殖技术(ART)的使用情况。

结果

共纳入405对夫妇。就诊时,男性的平均年龄为34.4(标准差±6.5)岁,女性为31.1(标准差±4.3)岁(P <.0001)。59%(198/334)的夫妇首次就诊医生是妇科医生,25%(83/334)的病例是生殖内分泌学家(REI),14%(47/334)的夫妇未经过先前的女性检查而是自行转诊,2%(6/334)的夫妇在就诊前同时看过妇科医生和REI。平均而言,夫妇在就诊前尝试怀孕22.3(标准差±21.1,范围0 - 120)个月。18%的夫妇在就诊前接受了ART。与就诊前未进行ART的夫妇相比,接受过ART的夫妇在VR前的总活动精子计数较低(P = 0.031)。大多数(70.4%)女性的检查无异常,使精索静脉曲张成为这对夫妇不孕的唯一可纠正因素。

结论

我们的研究结果显示,需要VR的不孕男性转诊存在显著延迟。18%的夫妇在进行费用低廉的男性检查之前就接受了昂贵的ART。在医疗费用控制的时代,尽早转诊至男性不育专家处至关重要。

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Surgery or embolization for varicoceles in subfertile men.对不育男性精索静脉曲张进行手术或栓塞治疗。
Cochrane Database Syst Rev. 2012 Oct 17;10:CD000479. doi: 10.1002/14651858.CD000479.pub5.

本文引用的文献

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Epidemiology of varicocele.精索静脉曲张的流行病学
Asian J Androl. 2016 Mar-Apr;18(2):179-81. doi: 10.4103/1008-682X.172640.

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