Huang Weihong, Qing Yujie, Wang Ningwei, Lu Yi, Liu Tianshu, Liu Tao, Yang Wenming, Li Songjun
School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China.
Entry-Exit Inspection Quarantine Bureau, Zhenjiang 212008, China.
Materials (Basel). 2018 Oct 23;11(11):2067. doi: 10.3390/ma11112067.
In this research, a novel, sulfamethazine, thermosensitive, molecularly-imprinted polymer (MIP) with an obvious core⁻shell structure for the enrichment of sulfamethazine (SMZ), which involved temperature sensitive monomer N-Isopropylacrylamide, functional monomer methacrylic acid and cross-linking agents ethyleneglycol dimethacrylate (EGDMA) and N,N'-methylenebisacrylamide, was successfully compounded using the surface polymerization method. To ensure the best experimental group, we designed and compared three groups of controlled experiments of MIPs with different crosslinking agents. When the adsorption temperature was almost the lower critical solution temperature (LCST) of Poly(N-Isopropylacrylamide), the preparative MIPs showed outstanding adsorption capacity and specific identification to sulfamethazine. Moreover, this allowed the MIPs to better facilitate by combining the template molecules, as well as optimizing the imprinting factor. In addition, after 80 min, the adsorption of the MIPs leveled off and remained constant, and the adsorption quantity reached (a maximum of) at 8.1 mg·g.
在本研究中，采用表面聚合法成功制备了一种新型的、具有明显核壳结构的磺胺二甲嘧啶热敏分子印迹聚合物（MIP），用于富集磺胺二甲嘧啶（SMZ），该聚合物涉及温度敏感单体N-异丙基丙烯酰胺、功能单体甲基丙烯酸以及交联剂乙二醇二甲基丙烯酸酯（EGDMA）和N,N'-亚甲基双丙烯酰胺。为确保最佳实验组，我们设计并比较了三组使用不同交联剂的MIPs对照实验。当吸附温度接近聚（N-异丙基丙烯酰胺）的最低临界溶液温度（LCST）时，制备的MIPs对磺胺二甲嘧啶表现出出色的吸附能力和特异性识别。此外，这使得MIPs通过结合模板分子以及优化印迹因子，能够更好地发挥作用。此外，80分钟后，MIPs的吸附趋于平稳并保持恒定，吸附量达到（最大值）8.1 mg·g。
