Dong Ruichen, Li Jinhua, Xiong Hua, Lu Wenhui, Peng Hailong, Chen Lingxin
State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China; Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Talanta. 2014 Dec;130:182-91. doi: 10.1016/j.talanta.2014.06.055. Epub 2014 Jul 6.
Thermosensitive molecularly imprinted polymers (T-MIPs) on porous carriers were prepared via the synergy of dual functional monomers of 4-vinylpyridine (VP) and N-isopropylacrylamide (NIPAM), for selective recognition and controlled adsorption and release of bisphenol A (BPA) by the temperature regulation. The porous polymer supporter was synthesized by multistep swelling of polystyrene and then both the NIPAM with temperature responsiveness and the basic monomers of VP were grafted on them in a simple way. The resultant T-MIPs showed high binding capacity, fast kinetics, and the adsorption processes were found to follow Langmuir-Freundlich isotherm and pseudo-second-order kinetic models. The adsorption capacity increased slightly along with the rise of temperature (such as 20°C) under lower critical solution temperature (LCST, 33°C) and decreased fast above LCST (such as 50°C). Subsequently, the T-MIPs were employed as novel adsorbents for selective solid-phase extraction (SPE) of BPA from seawater and yogurt samples. Satisfying recoveries in the range of 94.83-98.47% were obtained with the precision of 3.21% at ambient temperature (20°C). Through 6 adsorption-desorption cycles, the reusable T-MIPs exhibited a good recoverability with the relative standard error within 9.8%. The smart T-MIPs provided great potentials for selective identification, adsorption/release and removal of BPA by simple stimuli responsive regulation.
通过4-乙烯基吡啶（VP）和N-异丙基丙烯酰胺（NIPAM）双功能单体的协同作用，在多孔载体上制备了热敏分子印迹聚合物（T-MIPs），用于通过温度调节对双酚A（BPA）进行选择性识别以及控制吸附和释放。多孔聚合物载体通过聚苯乙烯的多步溶胀合成，然后将具有温度响应性的NIPAM和VP碱性单体以简单的方式接枝到其上。所得的T-MIPs表现出高结合容量、快速动力学，并且发现吸附过程遵循Langmuir-Freundlich等温线和准二级动力学模型。在较低临界溶液温度（LCST，33°C）下，吸附容量随着温度（如20°C）的升高而略有增加，而在LCST以上（如50°C）则快速下降。随后，T-MIPs被用作新型吸附剂，用于从海水和酸奶样品中选择性固相萃取（SPE）BPA。在环境温度（20°C）下，回收率在94.83-98.47%范围内，精密度为3.21%，令人满意。通过6次吸附-解吸循环，可重复使用的T-MIPs表现出良好的可回收性，相对标准误差在9.8%以内。这种智能T-MIPs通过简单的刺激响应调节，为BPA的选择性识别、吸附/释放和去除提供了巨大潜力。
