Zhu Chelsea, Sidiki Sabeen, Grider Brittany, Fink Brian, Hubbard Nicole, Mukundan Deepa
1 University of Toledo, Toledo, OH, USA.
2 ProMedica Toledo Hospital, Toledo, OH, USA.
Clin Pediatr (Phila). 2019 Feb;58(2):185-190. doi: 10.1177/0009922818809523. Epub 2018 Oct 26.
This study was a retrospective analysis of inpatient and emergency department (ED) data on respiratory pathogen panel (RPP) testing between December 16, 2013, and December 15, 2015, at a mid-sized children's hospital. We assessed whether RPP decreases antibiotic days of therapy and length of hospital stay for pediatric patients with acute respiratory infections. In the inpatient population, patients testing positive with RPP were given fewer antibiotic days of therapy (2.99 vs 4.30 days; P = .032) and had shorter hospital stays (2.84 vs 3.80 days; P = .055) than patients testing negative. In the ED population, patients testing positive with RPP received fewer discharge prescriptions for antibiotics than patients not tested (8.8% vs 41.1%; P < .001). RPP use was more prevalent in admitted patients than in ED patients (78.9% vs 7.3%; P < .001). Our results suggest that RPP testing curbs antibiotic use and decreases length of hospital stay.
本研究是对一家中型儿童医院2013年12月16日至2015年12月15日期间住院患者和急诊科（ED）呼吸道病原体检测（RPP）数据的回顾性分析。我们评估了RPP是否能减少急性呼吸道感染儿科患者的抗生素治疗天数和住院时间。在住院患者中，RPP检测呈阳性的患者抗生素治疗天数较少（2.99天对4.30天；P = 0.032），住院时间也较短（2.84天对3.80天；P = 0.055），而检测呈阴性的患者则相反。在急诊科患者中，RPP检测呈阳性的患者出院时开具的抗生素处方比未检测的患者少（8.8%对41.1%；P < 0.001）。RPP检测在住院患者中的使用比在急诊科患者中更为普遍（78.9%对7.3%；P < 0.001）。我们的结果表明，RPP检测可抑制抗生素的使用并缩短住院时间。
