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Advances in our understanding of the genetics of childhood neurodevelopmental disorders.

作者信息

Doherty Joanne, Cooper Miriam, Thapar Anita

机构信息

Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK.

Neurodevelopmental Service, Cwm Taf University Health Board, Merthyr Tydfil, UK.

出版信息

Evid Based Ment Health. 2018 Nov;21(4):171-172. doi: 10.1136/ebmental-2018-300067. Epub 2018 Oct 25.

DOI:10.1136/ebmental-2018-300067
PMID:30361329
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10270455/
Abstract
摘要

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本文引用的文献

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Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.发现首个与注意缺陷多动障碍全基因组显著相关的风险位点。
Nat Genet. 2019 Jan;51(1):63-75. doi: 10.1038/s41588-018-0269-7. Epub 2018 Nov 26.
2
Common variants at 2q11.2, 8q21.3, and 11q13.2 are associated with major mood disorders.常见变异位于 2q11.2、8q21.3 和 11q13.2 与主要心境障碍有关。
Transl Psychiatry. 2017 Dec 11;7(12):1273. doi: 10.1038/s41398-017-0019-0.
3
Copy Number Variation in Syndromic Forms of Psychiatric Illness: The Emerging Value of Clinical Genetic Testing in Psychiatry.精神疾病综合征形式中的拷贝数变异：临床基因检测在精神病学中的新兴价值。
Am J Psychiatry. 2017 Nov 1;174(11):1036-1050. doi: 10.1176/appi.ajp.2017.16080946.
4
Current evidence-based recommendations on investigating children with global developmental delay.关于对全面发育迟缓儿童进行调查的当前循证建议。
Arch Dis Child. 2017 Nov;102(11):1071-1076. doi: 10.1136/archdischild-2016-311271.
5
Psychiatric Genomics: An Update and an Agenda.精神科基因组学：最新进展与议程
Am J Psychiatry. 2018 Jan 1;175(1):15-27. doi: 10.1176/appi.ajp.2017.17030283. Epub 2017 Oct 3.
6
Schizophrenia and the neurodevelopmental continuum:evidence from genomics.精神分裂症与神经发育连续体：来自基因组学的证据
World Psychiatry. 2017 Oct;16(3):227-235. doi: 10.1002/wps.20440.
7
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.对超过16000名自闭症谱系障碍患者进行全基因组关联研究的荟萃分析，发现了一个位于10q24.32的新基因座，且与精神分裂症存在显著重叠。
Mol Autism. 2017 May 22;8:21. doi: 10.1186/s13229-017-0137-9. eCollection 2017.
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Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.普通人群中自闭症谱系障碍的遗传风险与神经精神变异
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