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阳极氧化或车削牙种植体?

Anodised or turned dental implants?

作者信息

Reis Natacha, Bergamini Marco, Silvestre Thamar, Veitz-Keenan Analia

机构信息

New York University, College of Dentistry, New York, USA.

出版信息

Evid Based Dent. 2018 Oct;19(3):80-81. doi: 10.1038/sj.ebd.6401325.

Abstract

Data sourcesAn electronic search without time or language restrictions was undertaken using several databases: PubMed/Medline, Web of Science and the Cochrane Oral Health Group Trials Register and ongoing clinical trials. Manual searches were performed in dental implant related journals and reference lists of identified studies, and relevant reviews were scanned for possible additional studies.Study selectionEligibility criteria included human clinical studies, either randomised or not, comparing implant failure rates, MBL and/or post-operative infection in any group of patients receiving turned (machined) and anodised-surface (TiUnite) implants, both from the same implant manufacturer.Data extraction and synthesisThe titles and abstracts of all reports identified through the electronic searches were read independently by the three authors. For studies appearing to meet the inclusion criteria, or for which there were insufficient data in the title and abstract to make a clear decision, the full report was obtained. Disagreements were resolved by discussion between the authors. Quality assessment of the studies was executed according to the Newcastle-Ottawa scale (NOS), which is a quality assessment tool used when observational studies are also included in systematic reviews.ResultsThirty-eight publications were included. The results suggest a risk ratio =2.82(95%CI, 1.95 - 4.06, P < 0.00001) for failure of turned implants when compared to anodised-surface implants. Sensitivity analyses showed similar results when only the studies inserting implants in maxillae or mandibles were pooled. There were no statistically significant effects of turned implants on the MBL (mean difference [MD]=0.02, (95%CI, 0.16 - 0.20; P = 0 82) in comparison to anodised implants. The results of a meta-regression considering the follow-up period as a covariate suggested an increase of the MD with the increase in the follow-up time (MD increase 0.012 mm year 1), however, without a statistical significance (P = 0.813). Due to lack of satisfactory information, meta-analysis for the outcome 'post-operative infection' was not performed.ConclusionsWithin the limitations of the existing investigations, the present study suggests that turned implants have a statistically higher probability to fail than anodised-surface implants, regardless of whether the implants were placed in maxilla or mandible. There were no statistically significant effects of turned implants on the MBL when compared with anodised implants. A comparison of post-operative infection between the implant types was not possible, due to lack of sufficient information. The reliability and validity of the data collected, the limitations of the quality assessment tool and the potential for biases and confounding factors are some of the shortcomings of the present study. The results have to be interpreted with caution due to the presence of several confounding factors in the included studies.

摘要

数据来源

使用多个数据库进行了无时间或语言限制的电子检索

PubMed/Medline、科学网以及Cochrane口腔健康组试验注册库和正在进行的临床试验。在牙科植入物相关期刊和已识别研究的参考文献列表中进行了手动检索,并扫描相关综述以查找可能的其他研究。

研究选择

纳入标准包括人类临床研究,无论是否为随机研究,比较来自同一植入物制造商的机加工表面(TiUnite)植入物和阳极氧化表面植入物在任何患者组中的植入物失败率、边缘骨丢失(MBL)和/或术后感染情况。

数据提取与综合

三位作者独立阅读通过电子检索识别出的所有报告的标题和摘要。对于似乎符合纳入标准的研究,或者标题和摘要中数据不足无法做出明确决定的研究,获取完整报告。作者之间通过讨论解决分歧。根据纽卡斯尔 - 渥太华量表(NOS)对研究进行质量评估,该量表是在系统评价中纳入观察性研究时使用的质量评估工具。

结果

纳入了38篇出版物。结果表明,与阳极氧化表面植入物相比,机加工表面植入物失败的风险比为2.82(95%置信区间,1.95 - 4.06,P < 0.00001)。敏感性分析表明,仅汇总在上颌或下颌植入植入物的研究时,结果相似。与阳极氧化植入物相比,机加工表面植入物对MBL没有统计学上的显著影响(平均差异[MD]=0.02,(95%置信区间,0.16 - 0.20;P = 0.82)。将随访期作为协变量的元回归结果表明,MD随随访时间增加而增加(MD每年增加0.012 mm),然而,无统计学意义(P = 0.813)。由于缺乏令人满意的信息,未对“术后感染”结果进行荟萃分析。

结论

在现有研究的局限性内,本研究表明,无论植入物是放置在上颌还是下颌,机加工表面植入物在统计学上比阳极氧化表面植入物有更高的失败概率。与阳极氧化植入物相比,机加工表面植入物对MBL没有统计学上的显著影响。由于缺乏足够信息,无法比较不同类型植入物的术后感染情况。本研究的一些缺点包括所收集数据的可靠性和有效性、质量评估工具的局限性以及存在偏差和混杂因素的可能性。由于纳入研究中存在多个混杂因素,结果必须谨慎解释。

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