Soon Chun Hyang University Bucheon Hospital, Bucheon, Korea.
Seoul National University Boramae Medical Center, Seoul, Korea.
J Clin Hypertens (Greenwich). 2018 Dec;20(12):1724-1730. doi: 10.1111/jch.13417. Epub 2018 Oct 25.
This study was performed to investigate the association between four BP measurements (systolic blood pressure [SBP], diastolic blood pressure [DBP], mean arterial pressure [MAP], and pulse pressure [PP]) and four TOD parameters (left ventricular mass index [LVMI], E/e', estimated glomerular filtration rate [eGFR], and obstructive coronary artery disease [CAD]). Data were obtained from a nation-wide registry, composed of 652 patients (471 women, 58.4 ± 10.5 years) with suspected CAD who underwent elective invasive coronary angiography (CAG). A total of 217 patients (33.2%) had obstructive CAD (≥50%). In multivariable analyses, E/e' was associated with SBP, MAP and PP, and CAD was associated with SBP and PP (P < 0.05 for each). All four BP measurements were not associated with LVMI and eGFR (P > 0.05 for each). In patients undergoing elective invasive CAG, SBP, and PP had stronger relationships with E/e' and CAD than DBP and MAP.
本研究旨在探讨四项血压测量值（收缩压[SBP]、舒张压[DBP]、平均动脉压[MAP]和脉压[PP]）与四项 TOD 参数（左心室质量指数[LVMI]、E/e'、估算肾小球滤过率[eGFR]和阻塞性冠状动脉疾病[CAD]）之间的关联。数据来自一个由 652 名疑似 CAD 患者（471 名女性，58.4±10.5 岁）组成的全国性登记处，这些患者接受了选择性有创冠状动脉造影（CAG）。共有 217 名患者（33.2%）存在阻塞性 CAD（≥50%）。在多变量分析中，E/e'与 SBP、MAP 和 PP 相关，CAD 与 SBP 和 PP 相关（P<0.05）。四项血压测量值均与 LVMI 和 eGFR 无关（P>0.05）。在接受选择性有创 CAG 的患者中，SBP 和 PP 与 E/e'和 CAD 的关系比 DBP 和 MAP 更强。
