Theuring F, Ucer U, Hansmann I
Biol Reprod. 1987 May;36(4):825-8. doi: 10.1095/biolreprod36.4.825.
High affinity binding sites for luteinizing hormone-releasing hormone (LHRH) were characterized in Djungarian hamsters. Scatchard analysis was used to demonstrate specific LHRH-binding in hamster and, serving as controls, rat pituitaries (dissociation constant, KD = 0.6 nM, binding capacity, BM = 2.5 +/- 0.7 fmol/mg tissue; KD = 0.6 nM, BM = 6.9 +/- 1.9 fmol/mg tissue, respectively). In contrast to results obtained with rat ovaries (KD = 0.9 nM, BM = 3.0 +/- 0.9 fmol/mg tissue), no specific LHRH-binding was detected in hamster ovaries. Thus, it seems that direct gonadal action of LHRH in the Djungarian hamster is not involved in ovarian regulation.
在中仓鼠中对促黄体生成激素释放激素（LHRH）的高亲和力结合位点进行了表征。采用Scatchard分析来证明仓鼠垂体中存在特异性LHRH结合，并以大鼠垂体作为对照（解离常数KD = 0.6 nM，结合容量BM = 2.5±0.7 fmol/mg组织；KD = 0.6 nM，BM = 6.9±1.9 fmol/mg组织）。与大鼠卵巢的结果（KD = 0.9 nM，BM = 3.0±0.9 fmol/mg组织）相反，在中仓鼠卵巢中未检测到特异性LHRH结合。因此，LHRH在中仓鼠中的直接性腺作用似乎不参与卵巢调节。
