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腹腔干狭窄导致肝移植缺血性坏死的延迟诊断:通过频谱多普勒检查结果进行诊断

Delayed diagnosis of celiac stenosis causing hepatic transplant ischaemic necrosis: diagnosis by spectral Doppler findings.

作者信息

Sun Mark, Jeffrey R Brooke, DiMaio Michael A, Olcott Eric W

机构信息

Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA.

Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.

出版信息

BJR Case Rep. 2016 Oct 11;3(1):20150210. doi: 10.1259/bjrcr.20150210. eCollection 2017.

Abstract

Following presentation with abnormal liver function enzymes, confusion and fatigue, a 65-year-old male with alcoholic cirrhosis underwent spectral Doppler sonography that showed tardus parvus-like morphology in the main and left hepatic arteries, although peak systolic velocities and resistive indices remained normal. The patient's continuing clinical symptoms prompted CT angiography, which demonstrated an unexpected, haemodynamically significant stenosis of the celiac artery. Although the stenosis was successfully stented and the hepatic arterial waveforms normalized, the transplanted liver had already undergone ischaemic necrosis, with resulting failure and the need for retransplantation. Recognition of abnormal waveforms, despite normal peak systolic velocities and resistive indices, with prompt definitive imaging evaluation of the arterial tree beyond just the main hepatic artery, may lead to the diagnosis of unexpected flow-limiting lesions in time to allow revascularization and thus prevent ischaemic transplant failure.

摘要

一名65岁患有酒精性肝硬化的男性,在出现肝功能酶异常、意识模糊和疲劳症状后,接受了频谱多普勒超声检查,结果显示肝固有动脉和肝左动脉呈迟滞小峰样形态,尽管收缩期峰值流速和阻力指数仍正常。患者持续的临床症状促使其进行CT血管造影,结果显示腹腔动脉存在意外的、具有血流动力学意义的狭窄。尽管狭窄部位成功置入了支架且肝动脉波形恢复正常,但移植肝已发生缺血性坏死,最终导致肝功能衰竭,需要再次进行移植。尽管收缩期峰值流速和阻力指数正常,但识别异常波形,并及时对肝动脉主干以外的动脉树进行明确的影像学评估,可能会及时诊断出意外的血流限制性病变,从而实现血管重建,预防移植肝缺血性衰竭。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac2/6159272/bc1a20aab7b9/bjrcr.20150210.g001.jpg

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