Suppr超能文献

张力障碍性假性足下垂

Dystonic Pseudo Foot Drop.

作者信息

Aquino Camila C, Slow Elizabeth, Lang Anthony E

机构信息

Morton and Gloria Shulman Movement Disorders Center and the Edmond J. Safra Program in Parkinson's Disease Toronto Western Hospital Toronto Ontario Canada.

出版信息

Mov Disord Clin Pract. 2015 May 9;2(3):295-298. doi: 10.1002/mdc3.12174. eCollection 2015 Sep.

Abstract

The most common presentation of foot dystonia in patients with Parkinson's disease (PD) or dystonia is inversion of the foot accompanied by flexion of the toes, with or without extension of the hallux. Less commonly, foot dystonia may mimic foot drop, as occurs with weakness of the dorsiflexors muscles, resulting in a pseudo foot drop. This has rarely been reported in the literature and has been poorly recognized, often leading to misdiagnosis and unnecessary investigations and treatment. We report 5 patients with dystonic pseudo foot drop, one of them diagnosed with early-onset PD, 2 with sporadic PD, and 2 with dystonia. Despite the steppage gait, their physical exam revealed normal strength, and no other explanation for a "foot drop" was found. It is important to recognize this phenomenology, which can be a clue to the diagnosis of early-onset PD, and may be responsive to levodopa in selected patients.

摘要

帕金森病(PD)或肌张力障碍患者足部肌张力障碍最常见的表现是足内翻并伴有足趾屈曲,拇趾可伴有或不伴有背伸。较少见的情况是,足部肌张力障碍可能类似足下垂,就像背屈肌肌无力时出现的那样,导致假性足下垂。这在文献中鲜有报道,且认识不足,常导致误诊以及不必要的检查和治疗。我们报告了5例肌张力障碍性假性足下垂患者,其中1例诊断为早发性PD,2例为散发性PD,2例为肌张力障碍。尽管有跨越步态,但他们的体格检查显示肌力正常,且未发现其他导致“足下垂”的原因。认识到这种现象很重要,它可能是早发性PD诊断的线索,并且在部分患者中可能对左旋多巴有反应。

相似文献

1
Dystonic Pseudo Foot Drop.张力障碍性假性足下垂
Mov Disord Clin Pract. 2015 May 9;2(3):295-298. doi: 10.1002/mdc3.12174. eCollection 2015 Sep.
3
[Dopa-responsive dystonia].[多巴反应性肌张力障碍]
Vojnosanit Pregl. 2009 Jan;66(1):29-34. doi: 10.2298/vsp0901029d.
4
Dystonia in Parkinson's disease.帕金森病中的肌张力障碍
J Neurol. 2006 Dec;253 Suppl 7:VII7-13. doi: 10.1007/s00415-006-7003-6.
7
9
GCH1 mutations in dopa-responsive dystonia and Parkinson's disease.GCH1 突变与多巴反应性肌张力障碍和帕金森病。
J Neurol. 2018 Aug;265(8):1860-1870. doi: 10.1007/s00415-018-8930-8. Epub 2018 Jun 14.

本文引用的文献

1
3
Adult-onset primary focal foot dystonia.成人起病的原发性局灶性足部肌张力障碍。
Parkinsonism Relat Disord. 2006 Jan;12(1):57-60. doi: 10.1016/j.parkreldis.2005.07.004. Epub 2005 Sep 9.
5
Dystonia and parkinsonism.肌张力障碍和帕金森综合征。
Parkinsonism Relat Disord. 2001 Oct;8(2):109-21. doi: 10.1016/s1353-8020(01)00025-6.
9
Dystonic foot response of Parkinsonism.帕金森病的张力障碍性足部反应。
Arch Neurol. 1980 Mar;37(3):132-6. doi: 10.1001/archneur.1980.00500520030003.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验