McKean David, Kothari Alpesh, Chen Jane, Sidebottom Richard, Chan Victoria, Yanny Sarah, Teh James L
Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, Aylesbury, UK.
Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Trust, Oxford, UK.
BJR Case Rep. 2016 May 28;2(2):20150405. doi: 10.1259/bjrcr.20150405. eCollection 2016.
Pagetic vertebral ankylosis is an uncommon presentation and occurs when Paget's disease is associated with diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis. In these cases, the pagetic trait extends from one vertebra to another by invasion of the intervertebral disc space. Such acquired vertebral ankylosis is extremely uncommon but possible when bony bridging syndesmophytes or osteophytes are present. We describe one such case, where a delayed diagnosis resulted in the most extensive pagetic vertebral ankylosis described in the literature and severe patient morbidity.
畸形性骨炎所致脊柱强直性骨化是一种罕见的表现,当畸形性骨炎与弥漫性特发性骨肥厚和强直性脊柱炎相关联时发生。在这些病例中,畸形性骨炎的特征通过椎间盘间隙的侵犯从一个椎体延伸至另一个椎体。这种后天性脊柱强直性骨化极为罕见,但当存在骨桥连韧带骨赘或骨赘时是有可能发生的。我们描述了这样一例病例,其中延迟诊断导致了文献中所描述的最广泛的畸形性骨炎所致脊柱强直性骨化以及患者的严重发病情况。