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本文引用的文献

1
Efficacy and Feasibility of Salvage Living Donor Liver Transplantation after Initial Liver Resection in Patients with Hepatocellular Carcinoma.肝细胞癌患者初次肝切除术后挽救性活体肝移植的疗效与可行性
Dig Surg. 2016;33(1):8-14. doi: 10.1159/000441397. Epub 2015 Nov 10.
2
Salvage liver transplantation for hepatocellular carcinoma recurrence after primary liver resection.原发性肝切除术后肝细胞癌复发的挽救性肝移植
Clin Res Hepatol Gastroenterol. 2015 Feb;39(1):93-7. doi: 10.1016/j.clinre.2014.07.006. Epub 2014 Aug 21.
3
Salvage liver transplantation for recurrent hepatocellular carcinoma after liver resection: retrospective study of the Milan and Hangzhou criteria.肝切除术后复发性肝细胞癌的挽救性肝移植：米兰标准和杭州标准的回顾性研究
PLoS One. 2014 Jan 27;9(1):e87222. doi: 10.1371/journal.pone.0087222. eCollection 2014.
4
Short- and long-term outcomes after salvage liver transplantation versus primary liver transplantation for hepatocellular carcinoma: a meta-analysis.肝细胞癌挽救性肝移植与原位肝移植后的短期和长期结局：一项荟萃分析
Transplant Proc. 2013 Nov;45(9):3329-42. doi: 10.1016/j.transproceed.2013.06.004.
5
Systematic review of efficacy and outcomes of salvage liver transplantation after primary hepatic resection for hepatocellular carcinoma.原发性肝癌肝切除术后挽救性肝移植的疗效和结局的系统评价。
J Gastroenterol Hepatol. 2014 Jan;29(1):31-41. doi: 10.1111/jgh.12399.
6
Salvage living-donor liver transplantation to previously hepatectomized hepatocellular carcinoma patients: is it a reasonable strategy?对既往接受过肝切除术的肝细胞癌患者进行挽救性活体肝移植：这是一种合理的策略吗？
Hepatobiliary Pancreat Dis Int. 2013 Feb;12(1):10-1. doi: 10.1016/s1499-3872(13)60001-6.
7
Liver transplantation for hepatocellular carcinoma recurrence after liver resection: why deny this chance of cure?肝切除术后肝癌复发行肝移植：为何拒绝这一治愈机会？
J Clin Gastroenterol. 2013 Apr;47(4):352-8. doi: 10.1097/MCG.0b013e31826e6caf.
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Salvage liver transplantation for recurrent hepatocellular carcinoma within UCSF criteria after liver resection.UCSF 标准范围内肝切除术后复发肝细胞癌的挽救性肝移植。
PLoS One. 2012;7(11):e48932. doi: 10.1371/journal.pone.0048932. Epub 2012 Nov 8.
9
Salvage liver transplantation for patients with recurrent hepatocellular carcinoma after curative resection.根治性切除术后复发肝细胞癌患者的挽救性肝移植。
PLoS One. 2012;7(7):e41820. doi: 10.1371/journal.pone.0041820. Epub 2012 Jul 26.
10
Recipient outcomes of salvage liver transplantation versus primary liver transplantation: a systematic review and meta-analysis.挽救性肝移植与原发性肝移植的受者结局：系统评价和荟萃分析。
Liver Transpl. 2012 Nov;18(11):1316-23. doi: 10.1002/lt.23521.

肝细胞癌的挽救性肝移植：挽救与益处。

Salvage liver transplant for hepatocellular carcinoma: rescues and benefits.

作者信息

Zheng Shusen, Xie Qinfen, Cheng Jinkun

机构信息

Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University, Hangzhou 310006, China.

Department of Hepatobiliary and Pancreatic Surgery, Shulan (Hangzhou) Hospital, Hangzhou 310004, China.

出版信息

Transl Gastroenterol Hepatol. 2018 Sep 17;3:65. doi: 10.21037/tgh.2018.09.06. eCollection 2018.

DOI:10.21037/tgh.2018.09.06
PMID:30363838
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6182042/
Abstract

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in China, primary liver transplantation (PLT) and hepatic resection are thought to be the prime and more reasonable treatment. But due to the situation of donor shortage and a higher risk of tumor recurrence, salvage liver transplantation (SLT) is gradually being applied to the patients with HCC, and is confirmed as an effective and feasible treatment for patients. However, the indications and transplantation criteria for SLT still remain controversial. This article reviews the benefits and controversies of SLT and provides an effective reference for the clinical practice.

摘要

肝细胞癌（HCC）是中国最常见的恶性肿瘤之一，原位肝移植（PLT）和肝切除术被认为是主要且更合理的治疗方法。但由于供体短缺的情况以及肿瘤复发风险较高，挽救性肝移植（SLT）正逐渐应用于HCC患者，并被确认为对患者有效的可行治疗方法。然而，SLT的适应症和移植标准仍存在争议。本文综述了SLT的益处和争议，为临床实践提供有效参考。