Agasthi Pradyumna, Narayanasamy Hemalatha, Sorajja Dan, Slack James, Mookadam Farouk
Department of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USA.
Department of Cardio-Oncology, Mayo Clinic, Arizona 85259, USA.
Case Rep Cardiol. 2018 Sep 30;2018:3953579. doi: 10.1155/2018/3953579. eCollection 2018.
Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient presented with new heart failure symptoms and an ejection fraction decline.
地西他滨是核苷胞苷的嘧啶类似物,用于治疗骨髓增生异常综合征、慢性粒细胞白血病和急性粒细胞白血病。我们报告一例与用于继发性急性粒细胞白血病的地西他滨相关的心肌病病例。该患者出现了新的心力衰竭症状且射血分数下降。