Oda Seitaro, Kawano Yawara, Okuno Yutaka, Utsunomiya Daisuke, Nakaura Takeshi, Tsujita Kenichi, Yamashita Yasuyuki
Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan.
Departments of Hematology, Rheumatology, and Infectious Disease, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Radiol Case Rep. 2018 Oct 18;14(1):72-74. doi: 10.1016/j.radcr.2018.09.025. eCollection 2019 Jan.
Late gadolinium enhancement imaging by cardiac magnetic resonance imaging (CMR) is the most reliable method for identifying cardiac involvement in patients with amyloidosis, and myocardial T1 mapping is a novel CMR technique that enables the noninvasive detection and quantification of myocardial amyloid burden. Although, base-to-apex gradient patterns of impairment in patients with cardiac amyloidosis have been reported on myocardial strain analysis using echocardiography, we could not find any other reports to demonstrate that myocardial T1 mapping on CMR can clearly identify a base-to-apex gradient pattern of cardiac impairment in a patient with cardiac amyloidosis.
心脏磁共振成像（CMR）延迟钆增强成像，是识别淀粉样变性患者心脏受累情况的最可靠方法，而心肌T1 mapping是一种新型CMR技术，可实现心肌淀粉样蛋白负荷的无创检测和定量分析。尽管已有报道称，通过超声心动图进行心肌应变分析时，心脏淀粉样变性患者存在从心底到心尖的损伤梯度模式，但我们未发现其他报告表明CMR上的心肌T1 mapping能够明确识别心脏淀粉样变性患者从心底到心尖的心脏损伤梯度模式。
