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疑似脑膜炎病例诊断简化方法的提议:巴西皮奥伊州一家参考服务机构2007 - 2016年的经验报告

Proposal for a simplified approach to suspected meningitis case diagnosis: experience report of a reference service in the state of Piauí, Brazil, 2007-2016.

作者信息

Vieira Marcelo Adriano da Cunha E Silva, Lima Neto Adelino Soares, Costa Carlos Henrique Nery, Costa Dorcas Lamounier, Amaral Elna Joelane Lopes da Silva do, Batista Francisca Miriane de Araújo, Nascimento Gildevane Vieira do, Lima Joana Carolina Viana, Sousa Juana Victória Brandão de, Eulálio Kelsen Dantas, Campelo Lidianny Lauritzen Dias, Rodrigues Maria das Dores Rocha, Santos Mariana Oliveira, Almeida Neto Walfrido Salmito de

机构信息

Secretaria de Estado da Saúde do Piauí, Instituto de Doenças Tropicais Natan Portella, Teresina, PI, Brasil.

Secretaria de Estado da Saúde do Piauí, Laboratório Central de Saúde Pública Dr. Costa Alvarenga, Teresina, PI, Brasil.

出版信息

Epidemiol Serv Saude. 2018 Oct 22;27(3):e2017329. doi: 10.5123/S1679-49742018000300007.

DOI:10.5123/S1679-49742018000300007
PMID:30365697
Abstract

OBJECTIVE

to describe a simplified protocol to diagnose suspected cases of meningitis.

METHODS

this is an experience report on the approach to diagnosing meningitis at the Tropical Diseases Reference Service in the state of Piauí, Brazil, between 2007 and 2016; information was extracted from the Notifiable Diseases Information System (SINAN) and the laboratory record book; the chi-square test was used to compare epidemiological surveillance indicators based on final meningitis case classification; the Phi coefficient was used to verify the correlation between presumed diagnosis and laboratory-confirmed diagnosis.

RESULTS

considering the 4,096 cases of meningitis investigated, there was a reduction in the generic classification of meningitis cases from 72% to 47% (p<0.001); indicated laboratory investigation profile showed agreement with final meningitis case diagnosis. (rf=0.66; p<0.001).

CONCLUSION

a greater proportion of specific etiologic diagnosis of meningitis was achieved while the protocol was in use.

摘要

目的

描述一种诊断疑似脑膜炎病例的简化方案。

方法

这是一份关于2007年至2016年巴西皮奥伊州热带病参考服务中心诊断脑膜炎方法的经验报告;信息从法定传染病信息系统(SINAN)和实验室记录簿中提取;采用卡方检验根据最终脑膜炎病例分类比较流行病学监测指标;使用Phi系数验证推定诊断与实验室确诊诊断之间的相关性。

结果

考虑到所调查的4096例脑膜炎病例,脑膜炎病例的总体分类从72%降至47%(p<0.001);所示实验室检查概况与最终脑膜炎病例诊断相符。(rf=0.66;p<0.001)。

结论

在使用该方案期间,脑膜炎的特定病因诊断比例更高。

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