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构建并初步测试一种新型前列腺磁共振成像/超声融合活检模型。

Constructing and Pilot Testing a Novel Prostate Magnetic Resonance Imaging/Ultrasound Fusion Biopsy Phantom.

作者信息

Caldwell Brandon, Greenwald David, Moreira Daniel, Tain Rong-Wen, Coogan Christopher, Xie Karen, Mar Winnie, Pfanner Peter, Abern Michael

机构信息

Department of Urology, University of Illinois at Chicago College of Medicine, Chicago, IL.

Department of Urology, University of Illinois at Chicago College of Medicine, Chicago, IL.

出版信息

Urology. 2019 Feb;124:33-37. doi: 10.1016/j.urology.2018.10.029. Epub 2018 Oct 24.

DOI:10.1016/j.urology.2018.10.029
PMID:30366044
Abstract

OBJECTIVE

To describe the design and build of a novel phantom for magnetic resonance imaging (MRI)/ultrasound (US) fusion biopsy and present pilot testing results from a multicenter urology resident training session.

METHODS

We cast our phantom from polyvinylchloride-plastisol that features 10 mm and 5 mm blue clay tumors, a urethral lumen, and an echogenic capsule. T2-weighted images were acquired with a 3T MR750 scanner (GE Healthcare, Boston, MA). Fusion testing was performed on the bkFusion system (BK ultrasound, Peabody, MA) with MIM Symphony software (MIM, Cleveland, OH) and an 18-gauge Bard Monopty disposable gun (Bard, Murray Hill, NJ). Twenty residents from 6 urology programs in Chicago performed proctored user testing.

RESULTS

The per phantom material cost was $12. The phantom was compatible with all necessary equipment to create a MRI/US fusion data set. MRI and US imaging characteristics were excellent with hypointense lesions. Image fusion was achieved through both end and side fire ultrasound probes. The phantom allowed for biopsies to be performed, and target lesion hits were confirmed by visual inspection of core samples. 38% (8/21) of urology resident pilot testing participants had previously performed a fusion biopsy. The mean postsession survey scores were (1-10 [best]): realism 9.0, usefulness 9.4, ease of use 9.1, ease of orientation 8.9, and overall experience 9.3.

CONCLUSION

This simple and inexpensive phantom allows for training and accuracy testing of MRI/US fusion biopsy hardware and software platforms.

摘要

目的

描述一种用于磁共振成像(MRI)/超声(US)融合活检的新型体模的设计与构建,并展示多中心泌尿外科住院医师培训课程的初步测试结果。

方法

我们用聚氯乙烯增塑溶胶浇铸体模,其具有10毫米和5毫米的蓝色黏土肿瘤、尿道腔和一个回声增强的包膜。使用3T MR750扫描仪(通用电气医疗集团,马萨诸塞州波士顿)采集T2加权图像。在bkFusion系统(BK超声,马萨诸塞州皮博迪)上使用MIM Symphony软件(MIM,俄亥俄州克利夫兰)和18号巴德一次性穿刺活检枪(巴德,新泽西州默里山)进行融合测试。来自芝加哥6个泌尿外科项目的20名住院医师进行了有监督的用户测试。

结果

每个体模的材料成本为12美元。该体模与创建MRI/US融合数据集的所有必要设备兼容。MRI和US成像特征在低信号病变方面表现出色。通过端射和侧射超声探头均可实现图像融合。该体模允许进行活检,通过对芯样的目视检查确认了对目标病变的命中。38%(8/21)的泌尿外科住院医师试点测试参与者此前曾进行过融合活检。课后调查的平均得分(1 - 10分[最佳])为:逼真度9.0、有用性9.4、易用性9.1、定位容易度8.9和总体体验9.3。

结论

这种简单且廉价的体模可用于MRI/US融合活检硬件和软件平台的培训及准确性测试。

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