人类α-珠蛋白定位于16号染色体上PGP远端的pter-p13.3区域。
Human alpha-globin maps to pter-p13.3 in chromosome 16 distal to PGP.
作者信息
Breuning M H, Madan K, Verjaal M, Wijnen J T, Meera Khan P, Pearson P L
出版信息
Hum Genet. 1987 Jul;76(3):287-9. doi: 10.1007/BF00283625.
PMID:3036689
Abstract
Fibroblasts from a fetus with an unbalanced karyotype 46(XY), -16,+(16qter-16p13.3::4q31.1-4qter) were found to possess only one allele at the 3' hypervariable region (3'HVR) close to the alpha-globin locus and two alleles at the PGP locus. This places the alpha-globin locus at the very tip of 16p, distal to PGP.
摘要
来自一名核型不平衡的胎儿（46，XY，-16，+（16qter-16p13.3::4q31.1-4qter））的成纤维细胞，在靠近α-珠蛋白基因座的3'高变区（3'HVR）仅发现一个等位基因，而在PGP基因座发现两个等位基因。这表明α-珠蛋白基因座位于16p的最末端，在PGP的远端。
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