[富克斯内皮性角膜营养不良患者行后弹力层内皮角膜移植术10年：我们学到了什么？]
[10 years of Descemet membrane endothelial keratoplasty in Fuchs endothelial corneal dystrophy : What have we learned?].
作者信息
Matthaei M, Schrittenlocher S, Hos D, Siebelmann S, Bucher F, Schaub F, Hoerster R, Siggel R, Roters S, Heindl L M, Bachmann B, Cursiefen C
机构信息
Zentrum für Augenheilkunde, Universitätsklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland.
UCL Institute of Ophthalmology, University College London, London, Großbritannien.
出版信息
Ophthalmologe. 2019 Mar;116(3):236-242. doi: 10.1007/s00347-018-0800-3.
BACKGROUND AND OBJECTIVE
Descemet membrane endothelial keratoplasty (DMEK) has increased in popularity since its introduction over 10 years ago. This article presents a summary of the experiences of the past years collected at the Department of Ophthalmology at the University of Cologne.
METHODS
A literature review of DMEK studies primarily from the Department of Ophthalmology at the University of Cologne, Germany was carried out. Own experiences in the fields of donor selection and graft preparation, DMEK surgery, complication management and postoperative treatment are summarized.
RESULTS
Since the introduction of DMEK experience has been gained and ongoing improvements have occurred ranging from donor-recipient allocation to postoperative follow-up. These led to a better reproducibility of the intervention for the surgeon, to a better postoperative result and to a reduction of the complication rate.
DISCUSSION
The DMEK represents a safe and individualized procedure for endothelial transplantation for corneal endothelial dysfunction. Continuing development of the method leads to optimization and safer results.
背景与目的
自10多年前引入以来，Descemet膜内皮角膜移植术（DMEK）越来越受欢迎。本文总结了科隆大学眼科过去几年收集的经验。
方法
对主要来自德国科隆大学眼科的DMEK研究进行文献综述。总结了在供体选择与植片制备、DMEK手术、并发症管理及术后治疗等方面的自身经验。
结果
自引入DMEK以来，已积累了经验，且从供体-受体匹配到术后随访都在不断改进。这些改进提高了手术医生操作的可重复性，改善了术后效果并降低了并发症发生率。
讨论
DMEK是一种用于角膜内皮功能障碍的内皮移植安全且个体化的手术方法。该方法的持续发展带来了优化及更安全的结果。
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