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Passive heat therapy for cerebral protection: new ideas of age-old concepts.

作者信息

Coombs Geoff B, Tremblay Joshua C

机构信息

Centre for Heart, Lung and Vascular Health, University of British Columbia - Okanagan, Kelowna, British Columbia, Canada.

Cardiovascular Stress Response Laboratory, Queen's University, Kingston, Ontario, Canada.

出版信息

J Physiol. 2019 Jan;597(2):371-372. doi: 10.1113/JP277314. Epub 2018 Nov 22.

DOI:10.1113/JP277314
PMID:30367732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6332711/
Abstract
摘要

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Passive heat therapy for cerebral protection: new ideas of age-old concepts.用于脑保护的被动热疗法：古老概念的新见解。
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Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion.热休克预处理可能通过减轻氧化应激和能量消耗来预防中暑诱导的循环性休克和脑缺血。
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本文引用的文献

1
Passive heat therapy protects against endothelial cell hypoxia-reoxygenation via effects of elevations in temperature and circulating factors.被动热疗通过升高温度和循环因子的作用来防止内皮细胞缺氧再氧合。
J Physiol. 2018 Oct;596(20):4831-4845. doi: 10.1113/JP276559. Epub 2018 Sep 12.
2
Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood-brain barrier disruption after ischemic brain injury.热休克蛋白27在内皮细胞中的靶向过表达可改善缺血性脑损伤后的血脑屏障破坏。
Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1243-E1252. doi: 10.1073/pnas.1621174114. Epub 2017 Jan 30.
3
Sauna bathing is inversely associated with dementia and Alzheimer's disease in middle-aged Finnish men.在芬兰中年男性中，洗桑拿与痴呆症和阿尔茨海默病呈负相关。
Age Ageing. 2017 Mar 1;46(2):245-249. doi: 10.1093/ageing/afw212.
4
The protective effect of heat acclimation from hypoxic damage in the brain involves changes in the expression of glutamate receptors.热适应对大脑缺氧损伤的保护作用涉及谷氨酸受体表达的变化。
Temperature (Austin). 2014 Jul 1;1(1):57-65. doi: 10.4161/temp.29719. eCollection 2014 Apr-Jun.
5
Epigenetics and cytoprotection with heat acclimation.表观遗传学与热适应的细胞保护作用。
J Appl Physiol (1985). 2016 Mar 15;120(6):702-10. doi: 10.1152/japplphysiol.00552.2015. Epub 2015 Oct 15.
6
Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion.热休克预处理可能通过减轻氧化应激和能量消耗来预防中暑诱导的循环性休克和脑缺血。
Shock. 2005 Feb;23(2):161-7. doi: 10.1097/01.shk.0000150779.47107.d5.