Kerris Elizabeth J, Patregnani Jason T, Sharron Matthew, Sochet Anthony A
Pediatric Critical Care Medicine, Department of Medicine, Division of Critical Care Medicine, Children's National Health System, 111 Michigan Ave NW, Suite M4811, Washington, DC, 20010, USA.
Pediatric Cardiac Intensive Care Medicine, Department of Medicine Division of Cardiac Intensive Care Medicine, Children's National Health System, 111 Michigan Ave NW, Suite M4811, Washington, DC, 20010, USA.
Int J Pediatr Otorhinolaryngol. 2018 Dec;115:1-5. doi: 10.1016/j.ijporl.2018.09.004. Epub 2018 Sep 13.
To assess the frequency of post-procedural complications, medical interventions, and hospital costs associated with microlaryngobronchoscopy (MLB) in children prophylactically admitted for pediatric intensive care unit (PICU) monitoring for age ≤ 2 years.
We performed a single-center, retrospective, descriptive study within a 44-bed PICU in a stand-alone, tertiary, pediatric referral center. Inclusion criteria were age ≤2 years and pre-procedural selection of prophylactic PICU monitoring after MLB between January 2010 and December 2015. Children were excluded for existing tracheostomy, if undergoing concurrent non-otolaryngeal procedures, or if intubated at the time of PICU admission. Primary outcomes were the development of major and minor procedural complications and medical rescue interventions. Secondary outcomes were hospital cost and length of stay (LOS).
One hundred and eight subjects met inclusion criteria with a median age of 5.3 (IQR: 2.6-10.9) months. A majority (86%) underwent therapeutic instrumentation in addition to diagnostic MLB. There were no observed major complications or rescue interventions. Minor complications were noted within 5 h of monitoring and included isolated stridor (24%), desaturation <90% (10%), and nausea/emesis (8%). Minor interventions included supplemental oxygen via regular nasal cannula (39%), single-dose inhaled racemic epinephrine (19%), single-dose systemic corticosteroids (19%), or high flow nasal cannula (HFNC) therapy (4%). Save for two cases of HFNC, interventions were completed or discontinued within 5 h. Median PICU LOS was 1.1 days and median cost was $9650 (IQR: $8235- $14,861) per encounter. Estimated cost of same day observation in our post anesthesia care unit (PACU) following MLB without PICU admission is $1921 per encounter.
In children ≤ 2 years of age prophylactically admitted for PICU observation, we did not observe severe complications or major interventions after MLB. Minor interventions and complications were noted early during post-procedural monitoring. PICU monitoring was substantially more expensive than same-day PACU observation. Young age as the sole criteria for prophylactic PICU monitoring after diagnostic or therapeutic MLB may be unjustified when comparable, cost-conscious care can be achieved in a PACU setting. Prior to pre-procedural selection of PICU monitoring, we recommend a broad contextual risk assessment including a review of comorbidities, operative plan, and intended anesthetic exposure.
评估年龄≤2岁、预防性入住儿科重症监护病房(PICU)接受监测的儿童,在进行微喉镜支气管镜检查(MLB)后出现术后并发症、医疗干预措施及住院费用的发生频率。
我们在一家拥有44张床位的独立三级儿科转诊中心的PICU内进行了一项单中心回顾性描述性研究。纳入标准为年龄≤2岁,且在2010年1月至2015年12月期间,于MLB术前选择预防性PICU监测。若儿童已有气管造口术、正在接受非耳鼻喉科同期手术或在入住PICU时已插管,则予以排除。主要结局指标为发生严重和轻微手术并发症以及医疗救援干预措施。次要结局指标为住院费用和住院时间(LOS)。
108名受试者符合纳入标准,中位年龄为5.3(四分位间距:2.6 - 10.9)个月。大多数(86%)儿童除了接受诊断性MLB外,还接受了治疗性器械操作。未观察到严重并发症或救援干预措施。在监测的5小时内发现了轻微并发症,包括单纯喘鸣(24%)、血氧饱和度<90%(10%)以及恶心/呕吐(8%)。轻微干预措施包括通过普通鼻导管吸氧(39%)、单剂量吸入消旋肾上腺素(19%)、单剂量全身用糖皮质激素(19%)或高流量鼻导管(HFNC)治疗(4%)。除两例HFNC治疗外,干预措施均在5小时内完成或停止。PICU的中位住院时间为1.1天,每次就诊的中位费用为9650美元(四分位间距:8235 - 14861美元)。在我们的麻醉后护理单元(PACU),MLB术后未入住PICU进行当日观察的估计费用为每次就诊1921美元。
对于年龄≤2岁、预防性入住PICU观察的儿童,我们在MLB术后未观察到严重并发症或重大干预措施。在术后监测早期发现了轻微干预措施和并发症。PICU监测的费用明显高于当日PACU观察。当在PACU环境中能够实现可比的、注重成本的护理时,仅以年龄作为诊断性或治疗性MLB术后预防性PICU监测的唯一标准可能不合理。在术前选择PICU监测之前,我们建议进行全面的背景风险评估,包括对合并症、手术计划和预期麻醉暴露的审查。