Cooper Craig M, Checketts Jake X, Brame Lacy, Gray Harrison, Downs Jaye Bea, Vassar Matt
Oklahoma State University Center for Health Sciences, United States.
Oklahoma State University Center for Health Sciences, United States.
Int J Pediatr Otorhinolaryngol. 2018 Dec;115:89-93. doi: 10.1016/j.ijporl.2018.09.027. Epub 2018 Sep 27.
The ability of clinical practice guidelines to improve patient outcomes depends on the quality of evidence that they are built upon. Research into tonsillectomy in children is lacking, and the gaps in evidence were identified by guideline authors.
The objective of this study is to evaluate the extent that new research is addressing the gaps identified in the AAO-HNS Tonsillectomy in Children Guideline.
For each recommendation in the AAO-HNS guideline Tonsillectomy In Children, we created PICO (Participants, Intervention, Comparator, Outcome) questions and search strings. PubMed was searched to locate studies undertaken after the final literature search performed by the AAO-HNS work group. These studies were then extracted and analyzed.
This study is relevant to all invested in focusing otolaryngological research on questions which currently lack strong evidence.
Trials in tonsillectomy that started after the development of the AAO-HNS clinical practice guidelines.
The main outcome measures of this study is the extent to which tonsillectomy research is addressing the evidence gaps listed in the clinical practice guideline.
Of the 2519 studies included in our sample, 276 (11%) were relevant to the 18 recommendations made within the Tonsillectomy in Pediatric Patients clinical practice guideline. All but one of the recommendations was met by at least one study.
and Relevance: Our findings indicate that knowledge gaps within the guideline at publication may have since been addressed and a guideline update may thus be warranted.
NA.
临床实践指南改善患者预后的能力取决于其所依据的证据质量。关于儿童扁桃体切除术的研究较为缺乏，指南制定者已识别出证据方面的差距。
本研究的目的是评估新研究在多大程度上解决了美国耳鼻咽喉头颈外科学会（AAO-HNS）儿童扁桃体切除术指南中所识别出的差距。
对于AAO-HNS儿童扁桃体切除术指南中的每项建议，我们创建了PICO（研究对象、干预措施、对照措施、结局）问题及检索词。检索PubMed以查找AAO-HNS工作组进行最终文献检索之后开展的研究。然后对这些研究进行提取和分析。
本研究适用于所有致力于将耳鼻咽喉科研究聚焦于当前缺乏有力证据的问题的人员。
AAO-HNS临床实践指南发布后开始的扁桃体切除术试验。
本研究的主要结局指标是扁桃体切除术研究在多大程度上解决了临床实践指南中列出的证据差距。
在我们样本中的2519项研究中，276项（11%）与儿科患者扁桃体切除术临床实践指南中的18项建议相关。除一项建议外，其他所有建议均至少有一项研究涉及。
我们的研究结果表明，指南发布时存在的知识差距可能此后已得到解决，因此可能有必要更新指南。
不适用。
