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Missed opportunities to test the neuropsychiatric safety--and efficacy--of varenicline among smokers with substance use disorders.在患有物质使用障碍的吸烟者中，错过检测伐尼克兰神经精神安全性及疗效的机会。
Drug Alcohol Depend. 2018 Apr;185:245-247. doi: 10.1016/j.drugalcdep.2018.02.001. Epub 2018 Feb 22.
2
Varenicline versus nicotine patch with brief advice for smokers with substance use disorders with or without depression: effects on smoking, substance use and depressive symptoms.伐伦克林与尼古丁贴片联合简短建议用于伴有或不伴有抑郁的物质使用障碍吸烟者：对吸烟、物质使用和抑郁症状的影响。
Addiction. 2017 Oct;112(10):1808-1820. doi: 10.1111/add.13861. Epub 2017 Jul 4.
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Real-world effectiveness of varenicline versus nicotine replacement therapy in patients with and without psychiatric disorders.伐尼克兰与尼古丁替代疗法在有和没有精神疾病的患者中的真实世界有效性。
J Addict Med. 2015 May-Jun;9(3):169-76. doi: 10.1097/ADM.0000000000000111.
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Effect of varenicline on individual nicotine withdrawal symptoms: a combined analysis of eight randomized, placebo-controlled trials.伐尼克兰对个体尼古丁戒断症状的影响：八项随机、安慰剂对照试验的联合分析。
Nicotine Tob Res. 2013 Nov;15(11):1849-57. doi: 10.1093/ntr/ntt066. Epub 2013 May 21.
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Psychiatric adverse events in randomized, double-blind, placebo-controlled clinical trials of varenicline: a pooled analysis.随机、双盲、安慰剂对照临床试验中伐伦克林的精神不良事件：汇总分析。
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Neural Signatures of Cognitive Flexibility and Reward Sensitivity Following Nicotinic Receptor Stimulation in Dependent Smokers: A Randomized Trial.依赖吸烟者烟碱受体刺激后认知灵活性和奖励敏感性的神经特征：一项随机试验
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Observational study of safety and efficacy of varenicline for smoking cessation among Filipino smokers.菲律宾吸烟者使用伐伦克林戒烟的安全性和有效性观察性研究。
Curr Med Res Opin. 2011 Oct;27(10):1869-75. doi: 10.1185/03007995.2011.607436. Epub 2011 Aug 12.
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Mental health status of varenicline and bupropion users during a quit attempt compared to current smokers, other quitters, and non-smokers.与当前吸烟者、其他戒烟者和非吸烟者相比，伐尼克兰和安非他酮使用者在戒烟尝试期间的心理健康状况。
Drug Alcohol Depend. 2015 Sep 1;154:132-8. doi: 10.1016/j.drugalcdep.2015.06.028. Epub 2015 Jun 27.

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Achieving Smoking Cessation Among Persons with Opioid Use Disorder.实现阿片类药物使用障碍患者的戒烟目标。
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Morbidity and mortality in homeless individuals, prisoners, sex workers, and individuals with substance use disorders in high-income countries: a systematic review and meta-analysis.高收入国家无家可归者、囚犯、性工作者和药物滥用者的发病率和死亡率：系统评价和荟萃分析。
Lancet. 2018 Jan 20;391(10117):241-250. doi: 10.1016/S0140-6736(17)31869-X. Epub 2017 Nov 12.
2
Cigarette Smoking Cessation Intervention for Buprenorphine Treatment Patients.丁丙诺啡治疗患者的戒烟干预。
Nicotine Tob Res. 2018 Apr 2;20(5):628-635. doi: 10.1093/ntr/ntx113.
3
Varenicline versus nicotine patch with brief advice for smokers with substance use disorders with or without depression: effects on smoking, substance use and depressive symptoms.伐伦克林与尼古丁贴片联合简短建议用于伴有或不伴有抑郁的物质使用障碍吸烟者：对吸烟、物质使用和抑郁症状的影响。
Addiction. 2017 Oct;112(10):1808-1820. doi: 10.1111/add.13861. Epub 2017 Jul 4.
4
Cigarette Smoking Is Associated With Increased Risk of Substance Use Disorder Relapse: A Nationally Representative, Prospective Longitudinal Investigation.吸烟与物质使用障碍复发风险增加相关：一项具有全国代表性的前瞻性纵向调查。
J Clin Psychiatry. 2017 Feb;78(2):e152-e160. doi: 10.4088/JCP.15m10062.
5
Interventions for tobacco use cessation in people in treatment for or recovery from substance use disorders.针对正在接受物质使用障碍治疗或已康复的人群的戒烟干预措施。
Cochrane Database Syst Rev. 2016 Nov 23;11(11):CD010274. doi: 10.1002/14651858.CD010274.pub2.
6
Selection criteria limit generalizability of smoking pharmacotherapy studies differentially across clinical trials and laboratory studies: A systematic review on varenicline.选择标准对不同临床试验和实验室研究中吸烟药物治疗研究的普遍性限制不同：一项关于伐尼克兰的系统评价
Drug Alcohol Depend. 2016 Dec 1;169:180-189. doi: 10.1016/j.drugalcdep.2016.10.018. Epub 2016 Oct 22.
7
Current Cigarette Smoking Among Adults - United States, 2005-2015.当前美国成年人吸烟状况 - 2005-2015 年。
MMWR Morb Mortal Wkly Rep. 2016 Nov 11;65(44):1205-1211. doi: 10.15585/mmwr.mm6544a2.
8
Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial.在有和没有精神疾病的吸烟者中，评估伐伦克林、安非他酮和尼古丁贴片的神经精神安全性和疗效（EAGLES）：一项双盲、随机、安慰剂对照临床试验。
Lancet. 2016 Jun 18;387(10037):2507-20. doi: 10.1016/S0140-6736(16)30272-0. Epub 2016 Apr 22.
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Design considerations for a pilot trial using a novel approach for evaluating smoking-cessation medication in methadone-maintained smokers.使用新方法评估美沙酮维持治疗吸烟者戒烟药物的试点试验的设计考量
Contemp Clin Trials. 2016 Mar;47:334-9. doi: 10.1016/j.cct.2016.02.008. Epub 2016 Mar 2.
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Financial incentives to promote extended smoking abstinence in opioid-maintained patients: a randomized trial.促进阿片类药物维持治疗患者长期戒烟的经济激励措施：一项随机试验。
Addiction. 2016 May;111(5):903-12. doi: 10.1111/add.13264. Epub 2016 Jan 23.

Missed opportunities to test the neuropsychiatric safety--and efficacy--of varenicline among smokers with substance use disorders.

作者信息

Nahvi Shadi, Arnsten Julia H

机构信息

Departments of Medicine, and of Psychiatry & Behavioral Sciences, Albert Einstein College of Medicine / Montefiore Medical Center, 111 East 210th Street, Bronx, NY, USA,

Departments of Medicine, of Psychiatry & Behavioral Sciences, and of Epidemiology & Population Health, Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY, USA,

出版信息

Drug Alcohol Depend. 2018 Apr;185:245-247. doi: 10.1016/j.drugalcdep.2018.02.001. Epub 2018 Feb 22.

DOI:10.1016/j.drugalcdep.2018.02.001
PMID:30369710
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6201286/
Abstract
摘要