Commentary: Antidepressive effects of targeting ELK-1 signal transduction.
作者信息
Cho Chang-Hoon
机构信息
College of Health Science, Korea University, Seoul, South Korea.
出版信息
Front Mol Neurosci. 2018 Oct 12;11:384. doi: 10.3389/fnmol.2018.00384. eCollection 2018.
Abstract
摘要
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Commentary: Antidepressive effects of targeting ELK-1 signal transduction.评论：靶向ELK-1信号转导的抗抑郁作用
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本文引用的文献
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Nat Med. 2018 May;24(5):591-597. doi: 10.1038/s41591-018-0011-0. Epub 2018 May 7.
2
Up-regulation of SIRT6 in the hippocampus induced rats with depression-like behavior via the block Akt/GSK3β signaling pathway.海马体中SIRT6的上调通过阻断Akt/GSK3β信号通路诱导大鼠出现抑郁样行为。
Behav Brain Res. 2017 Apr 14;323:38-46. doi: 10.1016/j.bbr.2017.01.035. Epub 2017 Jan 24.
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Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells.组蛋白去乙酰化酶SIRT6在多发性骨髓瘤细胞DNA损伤反应中作用的证据。
Blood. 2016 Mar 3;127(9):1138-50. doi: 10.1182/blood-2015-06-649970. Epub 2015 Dec 16.
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Effect of chronic stress on short and long-term plasticity in dentate gyrus; study of recovery and adaptation.慢性应激对齿状回短期和长期可塑性的影响；恢复与适应的研究。
Neuroscience. 2014 Nov 7;280:121-9. doi: 10.1016/j.neuroscience.2014.09.005. Epub 2014 Sep 16.
5
The F-box protein FBXO25 promotes the proteasome-dependent degradation of ELK-1 protein.F -box 蛋白 FBXO25 促进 ELK-1 蛋白的蛋白酶体依赖性降解。
J Biol Chem. 2013 Sep 27;288(39):28152-62. doi: 10.1074/jbc.M113.504308. Epub 2013 Aug 12.
6
Centaurin-α1-Ras-Elk-1 signaling at mitochondria mediates β-amyloid-induced synaptic dysfunction.单体蛋白-α1-Ras Elk-1 信号转导至线粒体介导β-淀粉样蛋白诱导的突触功能障碍。
J Neurosci. 2013 Mar 20;33(12):5367-74. doi: 10.1523/JNEUROSCI.2641-12.2013.
7
Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode.在重度抑郁发作期间，应答者和不应答者患者表现出不同的外周转录特征。
Transl Psychiatry. 2012 Nov 13;2(11):e185. doi: 10.1038/tp.2012.112.
8
Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents.抑郁症病理生理学和治疗的信号通路：快速作用药物的新机制。
Trends Neurosci. 2012 Jan;35(1):47-56. doi: 10.1016/j.tins.2011.11.004.
9
Long-lasting behavioral responses to stress involve a direct interaction of glucocorticoid receptors with ERK1/2-MSK1-Elk-1 signaling.长期的应激行为反应涉及糖皮质激素受体与 ERK1/2-MSK1-Elk-1 信号的直接相互作用。
Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13806-11. doi: 10.1073/pnas.1104383108. Epub 2011 Aug 1.
10
Elk-1 a transcription factor with multiple facets in the brain.Elk-1：一种在大脑中具有多方面作用的转录因子。
Front Neurosci. 2011 Mar 16;5:35. doi: 10.3389/fnins.2011.00035. eCollection 2011.
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