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制备氟氯苯醚菊酯纳米胶囊及其控释性能和田间药效研究。

Preparation of cyflumetofen nanocapsules and study on the controlled release performance and its field efficacy.

机构信息

Key Laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing, China.

Academy of Agricultural Sciences, Southwest University, Chongqing, China.

出版信息

Pest Manag Sci. 2019 May;75(5):1354-1360. doi: 10.1002/ps.5253. Epub 2018 Dec 4.

Abstract

BACKGROUND

In this study, 5% cyflumetofen nanocapsules were prepared by interfacial polymerization with isophorone diisocyanate and polyethylene glycol as the reaction monomer, and tristyrylphenol polyoxyethylene ether (601-P) as the emulsifier. The physical, chemical and sustained release properties of cyflumetofen nanocapsules were characterized using scanning electron microscopy, field emission scanning electron microscopy, laser particle size analysis, Fourier transform infrared spectroscopy, contact angles testing and high-performance liquid chromatography.

RESULTS

The results indicated that cyflumetofen nanocapsules were spherical, with an average particle size of 100 nm, and an encapsulation efficiency and loading rate of 86% and 32%, respectively. The thermal and cold storage stabilities of cyflumetofen nanocapsules were good. Under high temperature, lower pH or a high core-wall ratio, nanoparticle release is faster. The field efficacy experiment indicated that the efficacy of cyflumetofen nanocapsules against Panonychus citri reached 97%, 30 days after spraying, significantly greater than that of a 20% cyflumetofen suspension.

CONCLUSION

It is important to increase the stability, lengthen the release period and improve the efficacy of cyflumetofen in cyflumetofen nanocapsules. © 2018 Society of Chemical Industry.

摘要

背景

本研究采用界面聚合法,以异佛尔酮二异氰酸酯和聚乙二醇为反应单体,三苯乙烯基苯酚聚氧乙烯醚(601-P)为乳化剂,制备了 5%的氟吡菌酰胺纳米胶囊。利用扫描电子显微镜、场发射扫描电子显微镜、激光粒度分析、傅里叶变换红外光谱、接触角测试和高效液相色谱对氟吡菌酰胺纳米胶囊的物理化学性质和缓释性能进行了表征。

结果

结果表明,氟吡菌酰胺纳米胶囊呈球形,平均粒径为 100nm,包封率和载药量分别为 86%和 32%。氟吡菌酰胺纳米胶囊的热稳定性和低温贮藏稳定性良好。在高温、较低 pH 值或较高核壳比的情况下,纳米颗粒的释放速度较快。田间药效试验表明,施药 30d 后氟吡菌酰胺纳米胶囊对柑橘全爪螨的防治效果达到 97%,显著高于 20%氟吡菌酰胺悬浮剂。

结论

提高氟吡菌酰胺纳米胶囊的稳定性、延长释放期、提高药效至关重要。 © 2018 英国化学学会。

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