1 Center of Innovation for Veteran-Centered and Value-Driven Care Veterans Affairs Puget Sound Health Care System Seattle WA.
2 Department of Medicine University of Washington Seattle WA.
J Am Heart Assoc. 2018 Oct 2;7(19):e010010. doi: 10.1161/JAHA.118.010010.
Background Cardiac rehabilitation (CR) is strongly recommended after percutaneous coronary intervention (PCI), but it is underused. We sought to evaluate CR participation variation after PCI and its association with mortality among veterans. Methods and Results Patients undergoing PCI between 2007 and 2011 were identified in the Veterans Affairs Clinical Assessment, Reporting, and Tracking database and followed up until January 25, 2017. We excluded patients who died within 30 days of PCI and calculated the percentage participating in ≥1 outpatient CR visits within 12 months after PCI. We constructed multivariable hierarchical logistic regression models for CR participation, clustered by facility. We estimated propensity scores for CR participation, matched participants and nonparticipants by propensity score, calculated mortality rates, and estimated the association with mortality using Cox proportional hazards models. Participation in CR after PCI was 6.9% (2986/43 319) and varied significantly by PCI facility (range, 0%-36%). After 6.1 years median follow-up, CR participants had a 33% lower mortality rate than all nonparticipants (3.8 versus 5.7 deaths/100 person-years; hazard ratio, 0.67; 95% confidence interval, 0.61-0.75; P<0.001) and a 26% lower mortality rate than 2986 propensity-matched nonparticipants (3.8 versus 5.1 deaths/100 person-years; hazard ratio, 0.74; 95% confidence interval, 0.65-0.84; P<0.001). Participants attending ≥36 sessions had the lowest mortality rate (2.4 deaths/100 person-years; hazard ratio, 0.47; 95% confidence interval, 0.36-0.60; P<0.001). Conclusions CR participation after PCI among veterans is low overall, with significant facility-level variation. CR participation is associated with lower mortality rates in veterans. Additional efforts are needed to promote CR participation after PCI among veterans.
心脏康复(CR)在经皮冠状动脉介入治疗(PCI)后强烈推荐,但使用率较低。我们旨在评估 PCI 后 CR 参与情况的变化及其与退伍军人死亡率的关系。
在退伍军人事务部临床评估、报告和跟踪数据库中确定了 2007 年至 2011 年间接受 PCI 的患者,并随访至 2017 年 1 月 25 日。我们排除了 PCI 后 30 天内死亡的患者,并计算了 PCI 后 12 个月内至少参加 1 次门诊 CR 访视的患者比例。我们构建了多变量分层逻辑回归模型,以评估 CR 参与情况,并按机构进行聚类。我们估计了 CR 参与的倾向评分,通过倾向评分匹配参与者和非参与者,计算死亡率,并使用 Cox 比例风险模型估计与死亡率的关联。PCI 后接受 CR 的比例为 6.9%(2986/43319),且各 PCI 机构之间差异显著(范围:0%-36%)。在中位随访 6.1 年后,CR 参与者的死亡率比所有非参与者低 33%(3.8 例/100 人年 vs 5.7 例/100 人年;风险比,0.67;95%置信区间,0.61-0.75;P<0.001),比 2986 名匹配的非参与者低 26%(3.8 例/100 人年 vs 5.1 例/100 人年;风险比,0.74;95%置信区间,0.65-0.84;P<0.001)。参加≥36 次会议的患者死亡率最低(2.4 例/100 人年;风险比,0.47;95%置信区间,0.36-0.60;P<0.001)。
退伍军人 PCI 后总体上 CR 参与率较低,且各机构间差异显著。CR 参与与退伍军人的死亡率降低相关。需要进一步努力促进退伍军人 PCI 后 CR 的参与。