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健康猫支气管镜下与非支气管镜下支气管肺泡灌洗的比较。

Comparison of bronchoscopic and nonbronchoscopic bronchoalveolar lavage in healthy cats.

作者信息

Hooi Kimberly S, Defarges Alice M, Sanchez Andrea L, Nykamp Stephanie G, Weese J Scott, Abrams-Ogg Anthony C G, Bienzle Dorothee

出版信息

Am J Vet Res. 2018 Nov;79(11):1209-1216. doi: 10.2460/ajvr.79.11.1209.

Abstract

OBJECTIVE To compare bronchoalveolar lavage (BAL) accomplished by use of a bronchoscopic (B-BAL) and a nonbronchoscopic (NB-BAL) technique in healthy cats. ANIMALS 12 healthy cats. PROCEDURES Two BALs were performed in a randomized order 2 weeks apart in each cat. Cats were anesthetized, and a 2.9-mm fiberoptic bronchoscope (B-BAL) or 8F red rubber catheter (NB-BAL) was wedged in a bronchus. Two 5-mL aliquots of saline (0.9% NaCl) solution were infused into the left and right caudal lung fields and aspirated manually with a 20-mL syringe. Proportion of BAL fluid (BALF) retrieved, depth of wedging, and anesthetic complications were recorded. Total nucleated cell count, differential cell count, and semiquantitative scores of cytologic slide quality were determined for all BALF samples. Results were compared with ANOVAs and Wilcoxon signed rank tests. RESULTS Proportion of retrieved BALF and depth of wedging were significantly greater for B-BAL than NB-BAL. Differential cell counts and cytologic slide quality did not differ significantly between techniques. Complications included transient hemoglobin desaturation (24/24 [100%] BALs) and prolonged anesthetic recovery time (4/24 [17%] BALs). Anesthetic recovery scores did not differ significantly between techniques. CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that NB-BAL was noninferior to B-BAL with regard to ease of performance, anesthetic variables, and cytologic slide quality for cats without clinical respiratory tract disease.

摘要

目的 比较在健康猫中使用支气管镜技术(B-BAL)和非支气管镜技术(NB-BAL)进行支气管肺泡灌洗(BAL)的效果。动物 12 只健康猫。方法 每只猫以随机顺序在相隔 2 周的时间进行两次 BAL。猫被麻醉后,将一根 2.9 毫米的纤维支气管镜(B-BAL)或 8F 红色橡胶导管(NB-BAL)楔入支气管。将两份 5 毫升的生理盐水(0.9% NaCl)溶液注入左、右肺尾叶区域,并用 20 毫升注射器手动抽吸。记录回收的支气管肺泡灌洗液(BALF)比例、楔入深度和麻醉并发症。对所有 BALF 样本测定总核细胞计数、细胞分类计数和细胞学涂片质量的半定量评分。结果通过方差分析和 Wilcoxon 符号秩检验进行比较。结果 B-BAL 的回收 BALF 比例和楔入深度显著高于 NB-BAL。两种技术之间的细胞分类计数和细胞学涂片质量无显著差异。并发症包括短暂性血红蛋白饱和度降低(24/24 [100%] 的 BAL)和麻醉恢复时间延长(4/24 [17%] 的 BAL)。两种技术之间的麻醉恢复评分无显著差异。结论及临床意义 结果表明,对于无临床呼吸道疾病的猫,NB-BAL 在操作简便性、麻醉变量和细胞学涂片质量方面不劣于 B-BAL。

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