Jiangsu Key Laboratory of Pesticide Science, College of Sciences, Nanjing Agricultural University, Nanjing 210095, China.
Molecules. 2018 Oct 26;23(11):2783. doi: 10.3390/molecules23112783.
Indazole-containing derivatives represent one of the most important heterocycles in drug molecules. Diversely substituted indazole derivatives bear a variety of functional groups and display versatile biological activities; hence, they have gained considerable attention in the field of medicinal chemistry. This review aims to summarize the recent advances in various methods for the synthesis of indazole derivatives. The current developments in the biological activities of indazole-based compounds are also presented.
含吲唑的衍生物是药物分子中最重要的杂环之一。取代多样的吲唑衍生物带有多种官能团,并表现出多样的生物活性;因此,它们在药物化学领域受到了广泛关注。本综述旨在总结吲唑衍生物的各种合成方法的最新进展。还介绍了基于吲唑的化合物的生物活性的最新进展。